Varaico: Literature-Extracted Genetic Variants

Gene:RAF1
Variant:p.T491A
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RAF1

NM_002880.4:p.T491A

Associated Papers

Allosteric activation of functionally asymmetric RAF kinase dimers.

Hu J et al.

Cell, 2013

Characterization of Ser338 phosphorylation for Raf-1 activation.

Zang M et al.

The Journal of Biological Chemistry, 2008

Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase.

Terai K et al.

Embo Reports, 2005

Membrane localization, oligomerization, and phosphorylation are required for optimal raf activation.

Goetz CA et al.

The Journal of Biological Chemistry, 2003

Regulation of Raf through phosphorylation and N terminus-C terminus interaction.

Chong H et al.

The Journal of Biological Chemistry, 2003

Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition.

Tran NH et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."