Varaico: Literature-Extracted Genetic Variants

Gene:RAN
Variant:p.G19V
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RAN

NM_006325.5:p.G19V

Associated Papers

Essential role of the small GTPase Ran in postnatal pancreatic islet development.

Xia F et al.

Plos One, 2011

Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP.

Dishinger JF et al.

Nature Cell Biology, 2010

Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1.

Yang J et al.

Genes & Development, 1998

Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization.

Lounsbury KM et al.

The Journal of Biological Chemistry, 1996

Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import.

Carey KL et al.

The Journal of Cell Biology, 1996

The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/RANBP1.

Richards SA et al.

The Journal of Biological Chemistry, 1995

A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.

Dasso M et al.

The Embo Journal, 1994

Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression.

Kornbluth S et al.

The Journal of Cell Biology, 1994

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."