Varaico: Literature-Extracted Genetic Variants

Gene:RARA
Variant:p.R272Q
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RARA

NM_000964.4:p.R272Q

Associated Papers

An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Lin J et al.

Frontiers in Immunology, 2022

36505399 (PubMed )
Supplement: Table_2.xlsx › vars

Genomic Abnormalities as Biomarkers and Therapeutic Targets in Acute Myeloid Leukemia.

Ribeiro S et al.

Cancers, 2021

Mutational landscape of patients with acute promyelocytic leukemia at diagnosis and relapse.

Iaccarino L et al.

American Journal of Hematology, 2019

The genetics and clinical characteristics of children morphologically diagnosed as acute promyelocytic leukemia.

Zhao J et al.

Leukemia, 2019

Mutations affecting both the rearranged and the unrearranged PML alleles in refractory acute promyelocytic leukaemia.

Iaccarino L et al.

British Journal of Haematology, 2016

Evaluating frequency of PML-RARA mutations and conferring resistance to arsenic trioxide-based therapy in relapsed acute promyelocytic leukemia patients.

Lou Y et al.

Annals of Hematology, 2015

Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo.

Zhou DC et al.

Blood, 2002

Mutations in the E-domain of RAR portion of the PML/RAR chimeric gene may confer clinical resistance to all-trans retinoic acid in acute promyelocytic leukemia.

Imaizumi M et al.

Blood, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."