Varaico: Literature-Extracted Genetic Variants

Gene:RASA1
Variant:p.E5Q
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RASA1

NM_002890.3:p.E5Q

Associated Papers

Direct K-Ras Inhibitors to Treat Cancers: Progress, New Insights, and Approaches to Treat Resistance.

Nussinov R et al.

Annual Review of Pharmacology and Toxicology, 2024

Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics.

Tripathi S et al.

Computational and Structural Biotechnology Journal, 2022

34976316 (PubMed )
Supplement: mmc1.docx

Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach.

McFall T et al.

Cell Reports, 2021

Costello syndrome: Clinical phenotype, genotype, and management guidelines.

Gripp KW et al.

American Journal of Medical Genetics. Part A, 2019

Clinical and Molecular Characteristics of NF1-Mutant Lung Cancer.

Redig AJ et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016

Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials.

Said R et al.

Oncotarget, 2014

Kinetic mechanisms of mutation-dependent Harvey Ras activation and their relevance for the development of Costello syndrome.

Wey M et al.

Biochemistry, 2013

Dermatological phenotype in Costello syndrome: consequences of Ras dysregulation in development.

Siegel DH et al.

The British Journal of Dermatology, 2012

Ras and Rap signaling in synaptic plasticity and mental disorders.

Stornetta RL et al.

The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry, 2011

The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders.

Aoki Y et al.

Human Mutation, 2008

Ampullary carcinoma-A genetic perspective.

Jayaramayya K et al.

Mutation Research. Reviews in Mutation Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."