Associated Papers
Clinical features and molecular genetics of patients with RASopathies: expanding the phenotype with rare genes and novel variants.
Yılmaz Uzman C et al.
European Journal of Pediatrics, 2024
Direct K-Ras Inhibitors to Treat Cancers: Progress, New Insights, and Approaches to Treat Resistance.
Nussinov R et al.
Annual Review of Pharmacology and Toxicology, 2024
Not too little, not too much: the impact of mutation types in Wiskott-Aldrich syndrome and RAC2 patients.
Hsu AP
Clinical and Experimental Immunology, 2023
Mutational landscape of K-Ras substitutions at 12th position-a systematic molecular dynamics approach.
S UK et al.
Journal of Biomolecular Structure & Dynamics, 2022
Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics.
Tripathi S et al.
Computational and Structural Biotechnology Journal, 2022
Optimized Anchor-Modified Peptides Targeting Mutated RAS Are Promising Candidates for Immunotherapy.
Baleeiro RB et al.
Frontiers in Immunology, 2022
HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase.
Hannan JP et al.
Analytical Biochemistry, 2021
Generation of KS-58 as the first K-Ras(G12D)-inhibitory peptide presenting anti-cancer activity in vivo.
Sakamoto K et al.
Scientific Reports, 2020
Kinetic Mechanism of Formation of Hyperactive Embryonic Ras in Cells.
Wey M et al.
Biochemistry, 2016
Interaction of a novel fluorescent GTP analogue with the small G-protein K-Ras.
Iwata S et al.
Journal of Biochemistry, 2016
Kinetic mechanisms of mutation-dependent Harvey Ras activation and their relevance for the development of Costello syndrome.
Wey M et al.
Biochemistry, 2013
KRAS mutations in colorectal cancer from Tunisia: relationships with clinicopathologic variables and data on TP53 mutations and microsatellite instability.
Aissi S et al.
Molecular Biology Reports, 2013
Dermatological phenotype in Costello syndrome: consequences of Ras dysregulation in development.
Siegel DH et al.
The British Journal of Dermatology, 2012
HRAS mutants identified in Costello syndrome patients can induce cellular senescence: possible implications for the pathogenesis of Costello syndrome.
Niihori T et al.
Journal of Human Genetics, 2011
Mutations in K-ras and epidermal growth factor receptor expression in Korean patients with stages III and IV colorectal cancer.
Lee WS et al.
International Journal of Surgical Pathology, 2011
Ras and Rap signaling in synaptic plasticity and mental disorders.
Stornetta RL et al.
The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry, 2011
p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities.
Yang XY et al.
Oncogene, 2009
The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders.
Aoki Y et al.
Human Mutation, 2008
Not All Kirsten Rat Sarcoma Viral Oncogene Homolog Mutations Predict Poor Survival in Patients With Unresectable Colorectal Liver Metastasis.
Lin Z et al.
Technology in Cancer Research & Treatment, 0