Associated Papers
How can same-gene mutations promote both cancer and developmental disorders?
Nussinov R et al.
Science Advances, 2022
Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics.
Tripathi S et al.
Computational and Structural Biotechnology Journal, 2022
34976316 (PubMed )
Supplement: mmc1.docx
Costello syndrome: Clinical phenotype, genotype, and management guidelines.
Gripp KW et al.
American Journal of Medical Genetics. Part A, 2019
Molecular characterization of colorectal cancer using whole-exome sequencing in a Taiwanese population.
Chang YS et al.
Cancer Medicine, 2019
RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.
Qutob N et al.
Scientific Reports, 2018
29330521 (PubMed )
Supplement: 41598_2017_18851_MOESM2_ESM.xlsx › TMA_samples_mutation_data
Kinetic mechanisms of mutation-dependent Harvey Ras activation and their relevance for the development of Costello syndrome.
Wey M et al.
Biochemistry, 2013
Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours - implications for personalised cancer medicine.
Smith G et al.
British Journal of Cancer, 2010
The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders.
Aoki Y et al.
Human Mutation, 2008
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