Varaico: Literature-Extracted Genetic Variants

Gene:RASA3
Variant:p.G125V
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RASA3

NM_007368.4:p.G125V

Associated Papers

Rasa3 regulates stage-specific cell cycle progression in murine erythropoiesis.

Brindley EC et al.

Blood Cells, Molecules & Diseases, 2021

Differential effects of RASA3 mutations on hematopoiesis are profoundly influenced by genetic background and molecular variant.

Robledo RF et al.

Plos Genetics, 2020

Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism.

Molina-Ortiz P et al.

Plos Genetics, 2018

The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling.

Battram AM et al.

The Journal of Biological Chemistry, 2017

RASA3 is a critical inhibitor of RAP1-dependent platelet activation.

Stefanini L et al.

The Journal of Clinical Investigation, 2015

Rasa3 controls megakaryocyte Rap1 activation, integrin signaling and differentiation into proplatelet.

Molina-Ortiz P et al.

Plos Genetics, 2014

Nonredundant functions for Ras GTPase-activating proteins in tissue homeostasis.

King PD et al.

Science Signaling, 2013

Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis.

Blanc L et al.

Proceedings of the National Academy of Sciences of the United States of America, 2012

The scat mouse model highlights RASA3, a GTPase activating protein, as a key regulator of vertebrate erythropoiesis and megakaryopoiesis.

Peters LL et al.

Small Gtpases, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."