Varaico: Literature-Extracted Genetic Variants

Gene:RASSF1
Variant:p.A133S
Back to variants list

RASSF1

NM_007182.5:p.A133S

Associated Papers

Ras association domain family member 1 (RASSF1): Molecular characteristics, clinical relevance and therapeutic interventions in cancer.

Iqbal MO et al.

Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2025

Genetic Variants in RASSF1 (rs2073498), SERPINE1 (rs1799889), and EFNA1 (rs12904) Are Associated with Susceptibility in Mexican Patients with Colorectal Cancer: Clinical Associations and Their Analysis In Silico.

Tovar-Jácome CJ et al.

Genes, 2025

ATR-hippo drives force signaling to nuclear F-actin and links mechanotransduction to neurological disorders.

Chatzifrangkeskou M et al.

Science Advances, 2025

The XPA Protein-Life under Precise Control.

Krasikova YS et al.

Cells, 2022

Association of RASSF1A Ala133Ser polymorphism with cancer risk: a updated meta-analysis involving 7362 subjects.

Yin G et al.

Nucleosides, Nucleotides & Nucleic Acids, 2022

RASSF1A Suppression as a Potential Regulator of Mechano-Pathobiology Associated with Mammographic Density in BRCA Mutation Carriers.

Reye G et al.

Cancers, 2021

Investigation of the relationship between CTLA4 and the tumor suppressor RASSF1A and the possible mediating role of STAT4 in a cohort of Egyptian patients infected with hepatitis C virus with and without hepatocellular carcinoma.

Ali NA et al.

Archives of Virology, 2021

Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.

Sebate B et al.

Plos One, 2021

33770142 (PubMed )
Supplement: pone.0249324.s003.xlsx › 8772__III-8__

Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia.

Fontana D et al.

Hemasphere, 2020

33196013 (PubMed )
Supplement: hs9-4-e497-s008.xlsx › Sheet1

Cumulative Evidence for Associations between Genetic Variants and Risk of Esophageal Cancer.

Li G et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2020

31969372 (PubMed )
Supplement: 10559965epi191281-sup-230715_3_supp_6000458_q3kstt.docx

XPA: DNA Repair Protein of Significant Clinical Importance.

Borszéková Pulzová L et al.

International Journal of Molecular Sciences, 2020

Tumor suppressor C-RASSF proteins.

Iwasa H et al.

Cellular and Molecular Life Sciences : Cmls, 2018

RASSF1A, RECK genotypes and haplotypes in Egyptian population with Hepatocellular carcinoma.

Abd-Elfatah G et al.

Immunology Letters, 2016

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.

Karageorgos I et al.

Human Genomics, 2015

26092435 (PubMed )
Supplement: 40246_2015_34_MOESM1_ESM.xlsx › FamilyA

Safeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks.

Pefani DE et al.

Cell Cycle (georgetown, Tex.), 2015

RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.

Pefani DE et al.

Nature Cell Biology, 2014

Association between RASSF1A Ala133Ser polymorphism and cancer susceptibility: a meta-analysis involving 8,892 subjects.

Bayram S

Asian Pacific Journal of Cancer Prevention : Apjcp, 2014

PLCɛ and the RASSF family in tumour suppression and other functions.

Chan JJ et al.

Advances in Biological Regulation, 2013

Different methylation and microRNA expression pattern in male and female familial breast cancer.

Pinto R et al.

Journal of Cellular Physiology, 2013

Polymorphism of A133S and promoter hypermethylation in Ras association domain family 1A gene (RASSF1A) is associated with risk of esophageal and gastric cardia cancers in Chinese population from high incidence area in northern China.

Zhou SL et al.

Bmc Cancer, 2013

Apoptosis gene polymorphisms and risk of prostate cancer: a hospital-based study of German patients treated with brachytherapy.

Meyer A et al.

Urologic Oncology, 2013

A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma.

Yee KS et al.

Cancer Research, 2012

RASSF1A Ala133Ser polymorphism is associated with increased susceptibility to hepatocellular carcinoma in a Turkish population.

Bayram S

Gene, 2012

RASSF1 Polymorphisms in Cancer.

Gordon M et al.

Molecular Biology International, 2012

RASSF1A and the rs2073498 Cancer Associated SNP.

Donninger H et al.

Frontiers in Oncology, 2011

Protein kinase A-mediated phosphorylation of the RASSF1A tumour suppressor at Serine 203 and regulation of RASSF1A function.

Richter AM et al.

European Journal of Cancer (oxford, England : 1990), 2010

Functional importance of RASSF1A microtubule localization and polymorphisms.

El-Kalla M et al.

Oncogene, 2010

The association between RASSF1 gene polymorphisms and lung cancer susceptibility among people in Hubei Province of China.

Xiao G et al.

Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban, 2009

Putative association of the single nucleotide polymorphisms in RASSF1A promoter with Korean lung cancer.

Sung JS et al.

Lung Cancer (amsterdam, Netherlands), 2008

[Association of single nucleotide polymorphism at interleukin-10 gene 1082 nt with the risk of gastric cancer in Chinese population].

Zhou SZ et al.

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, 2008

Genotyping panel for assessing response to cancer chemotherapy.

Dai Z et al.

Bmc Medical Genomics, 2008

18547414 (PubMed )
Supplement: 1755-8794-1-24-S1.xls › SNPs_selected_for_SNPlex_design

The Ras-association domain family (RASSF) members and their role in human tumourigenesis.

van der Weyden L et al.

Biochimica Et Biophysica Acta, 2007

Single nucleotide polymorphism at codon 133 of the RASSF1 gene is preferentially associated with human lung adenocarcinoma risk.

Kanzaki H et al.

Cancer Letters, 2006

Nore1 and RASSF1 regulation of cell proliferation and of the MST1/2 kinases.

Avruch J et al.

Methods in Enzymology, 2006

High frequency somatic mutations in RASSF1A in nasopharyngeal carcinoma.

Pan ZG et al.

Cancer Biology & Therapy, 2005

[Association of interleukin-1 gene polymorphism with gastric cancer in a high-risk area of China].

Hu S et al.

Di 1 Jun Yi Da Xue Xue Bao = Academic Journal of the First Medical College of Pla, 2004

[Relationship between polymorphism of IRF-3 gene codon 427 and esophageal cancer in Anyang population of China].

Zhang CF et al.

Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences, 2004

Nore1 inhibits tumor cell growth independent of Ras or the MST1/2 kinases.

Aoyama Y et al.

Oncogene, 2004

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."