Varaico: Literature-Extracted Genetic Variants

Gene:RB1
Variant:p.I680T
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RB1

NM_000321.3:p.I680T

Associated Papers

RB1-I680T mutation potentiates tumor growth and chemotherapy sensitivity in non-small cell lung cancer via derepressing E2F1 transcription.

Zhu Y et al.

Cell Communication and Signaling : Ccs, 2026

Concurrent genomic assessment of circulating tumour cells and ctDNA to guide therapy in metastatic breast cancer.

Allsopp RC et al.

Bmc Cancer, 2025

41351070 (PubMed )
Supplement: 12885_2025_15187_MOESM1_ESM.zip › Supp_Table_1.xlsx › Sheet1

Detection of hotspot mutations in oral cancer through Ion AmpliSeq™ cancer hotspot panel v.2.0: A circulating DNA fragmentomics approach in the Northeast Indian population.

Baiju DC et al.

Oral Oncology, 2025

Molecular and clinicopathological features of appendiceal mucinous neoplasms.

Yanai Y et al.

Virchows Archiv : an International Journal of Pathology, 2021

Mutational spectrum of tobacco associated oral squamous carcinoma and its therapeutic significance.

Batta N et al.

World Journal of Surgical Oncology, 2019

Accurate detection of KRAS, NRAS and BRAF mutations in metastatic colorectal cancers by bridged nucleic acid-clamp real-time PCR.

Nagakubo Y et al.

Bmc Medical Genomics, 2019

Monitoring of cancer patients via next-generation sequencing of patient-derived circulating tumor cells and tumor DNA.

Onidani K et al.

Cancer Science, 2019

Identification of novel mutations in FFPE lung adenocarcinomas using DEPArray sorting technology and next-generation sequencing.

Lee JW et al.

Journal of Applied Genetics, 2018

Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer.

Betancor-Fernández I et al.

Handbook of Experimental Pharmacology, 2018

Mutation Detection in Tumor-Derived Cell Free DNA Anticipates Progression in a Patient With Metastatic Colorectal Cancer.

de Figueiredo Barros BD et al.

Frontiers in Oncology, 2018

Application of a multi-gene next-generation sequencing panel to a non-invasive oesophageal cell-sampling device to diagnose dysplastic Barrett's oesophagus.

Katz-Summercorn A et al.

The Journal of Pathology. Clinical Research, 2017

29085666 (PubMed )
Supplement: CJP2-3-258-s005.xlsx › Sheet1

Wide spetcrum mutational analysis of metastatic renal cell cancer: a retrospective next generation sequencing approach.

Fiorentino M et al.

Oncotarget, 2017

Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.

Dallol A et al.

Journal of Translational Medicine, 2016

Highly Concordant Key Genetic Alterations in Primary Tumors and Matched Distant Metastases in Differentiated Thyroid Cancer.

Sohn SY et al.

Thyroid : Official Journal of the American Thyroid Association, 2016

Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.

Lee JY et al.

Oncotarget, 2015

26527317 (PubMed )
Supplement: oncotarget-06-43731-s002.xlsx › Table_S2
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."