Varaico: Literature-Extracted Genetic Variants

Gene:RBBP6
Variant:p.G547S
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RBBP6

NM_006910.5:p.G547S

Associated Papers

Clinical versus fixed warfarin dosing and the impact on quality of anticoagulation (The ClinFix trial).

Fahmi AM et al.

Clinical and Translational Science, 2024

Lessons learned from the influence of CYP2C9 genotype on warfarin dosing.

Tidbury N et al.

Expert Opinion on Drug Metabolism & Toxicology, 2023

Genomewide association analysis of warfarin dose requirements in Middle Eastern and North African populations.

El Rouby N et al.

Clinical and Translational Science, 2022

Genotype-Guided Dosing of Warfarin in Chinese Adults: A Multicenter Randomized Clinical Trial.

Guo C et al.

Circulation. Genomic and Precision Medicine, 2020

Using Pharmacogenetic Testing to Tailor Warfarin Therapy: The Singapore Experience and What the Future Holds.

Chang GS et al.

European Cardiology, 2020

Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study.

Jorgensen AL et al.

Bmc Medicine, 2019

Efficacy and Safety of Genotype-Guided Warfarin Dosing in the Chinese Population: A Meta-analysis of Randomized Controlled Trials.

Wang F et al.

Journal of Cardiovascular Pharmacology, 2019

Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial.

Syn NL et al.

Bmc Medicine, 2018

Personalized Anticoagulation: Optimizing Warfarin Management Using Genetics and Simulated Clinical Trials.

Ravvaz K et al.

Circulation. Cardiovascular Genetics, 2017

Genotype-guided dosing of warfarin through modeling and simulation.

Deng J et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2017

Effect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty: The GIFT Randomized Clinical Trial.

Gage BF et al.

Jama, 2017

Implementing Algorithm-Guided Warfarin Dosing in an Ethnically Diverse Patient Population Using Electronic Health Records and Preemptive CYP2C9 and VKORC1 Genetic Testing.

Obeng AO et al.

Clinical Pharmacology and Therapeutics, 2016

Clinical Application of Genotype-guided Dosing of Warfarin in Patients with Acute Stroke.

Šupe S et al.

Archives of Medical Research, 2015

Poor warfarin dose prediction with pharmacogenetic algorithms that exclude genotypes important for African Americans.

Drozda K et al.

Pharmacogenetics and Genomics, 2015

Using pharmacogenetics in real time to guide therapy: the warfarin example.

Aminkeng F

Clinical Genetics, 2014

Determinants of the over-anticoagulation response during warfarin initiation therapy in Asian patients based on population pharmacokinetic-pharmacodynamic analyses.

Ohara M et al.

Plos One, 2014

A randomized trial of genotype-guided dosing of warfarin.

Pirmohamed M et al.

The New England Journal of Medicine, 2013

Q: Should we use pharmacogenetic testing when prescribing warfarin?

Rouse M et al.

Cleveland Clinic Journal of Medicine, 2013

Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy.

Horne BD et al.

Thrombosis and Haemostasis, 2012

Using pharmacogenetics in real time to guide warfarin initiation: a clinician update.

Carlquist JF et al.

Circulation, 2011

A pharmacometric model describing the relationship between warfarin dose and INR response with respect to variations in CYP2C9, VKORC1, and age.

Hamberg AK et al.

Clinical Pharmacology and Therapeutics, 2010

Implementing genotype-guided antithrombotic therapy.

Seip RL et al.

Future Cardiology, 2010

Pharmacogenetics of coumarinic oral anticoagulants.

Manolopoulos VG et al.

Pharmacogenomics, 2010

A policy model to evaluate the benefits, risks and costs of warfarin pharmacogenomic testing.

Meckley LM et al.

Pharmacoeconomics, 2010

Retrospective modeling study of ChatGPT (GPT 4) warfarin dose adjustment in patients with INRs outside the therapeutic range.

Tezcan H et al.

Digital Health, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."