Associated Papers
The PIN1-p38-CtIP signalling axis protects stalled replication forks from deleterious degradation.
Vivalda F et al.
Nucleic Acids Research, 2025
Mechanism of BRCA1-BARD1 function in DNA end resection and DNA protection.
Ceppi I et al.
Nature, 2024
BaP/BPDE suppresses homologous recombination repair in human trophoblast cells to induce miscarriage: The roles of lnc-HZ08.
Chen W et al.
Environment International, 2024
Systematic investigation of BRCA1-A, -B, and -C complexes and their functions in DNA damage response and DNA repair.
Li S et al.
Oncogene, 2024
NUDT16 regulates CtIP PARylation to dictate homologous recombination repair.
Zhang Z et al.
Nucleic Acids Research, 2024
Human CtIP: A 'double agent' in DNA repair and tumorigenesis.
Mozaffari NL et al.
Seminars in Cell & Developmental Biology, 2021
CtIP-mediated alternative mRNA splicing fine-tunes the DNA damage response.
Prados-Carvajal R et al.
Rna (new York, N.y.), 2021
FANCJ helicase promotes DNA end resection by facilitating CtIP recruitment to DNA double-strand breaks.
Nath S et al.
Plos Genetics, 2020
CtIP is essential for early B cell proliferation and development in mice.
Liu X et al.
The Journal of Experimental Medicine, 2019
CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs.
Mohiuddin M et al.
Nucleic Acids Research, 2019
PLK1 targets CtIP to promote microhomology-mediated end joining.
Wang H et al.
Nucleic Acids Research, 2018
CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress.
Przetocka S et al.
Molecular Cell, 2018
Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair.
Yasuhara T et al.
Cell, 2018
ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair.
Chen G et al.
Nucleic Acids Research, 2018
BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation.
Isono M et al.
Cell Reports, 2017
BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres.
Badie S et al.
The Embo Journal, 2015
BRCA1, a 'complex' protein involved in the maintenance of genomic stability.
Savage KI et al.
The Febs Journal, 2015
BRCA1 accelerates CtIP-mediated DNA-end resection.
Cruz-García A et al.
Cell Reports, 2014
Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.
Barton O et al.
The Journal of Cell Biology, 2014
Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection.
Makharashvili N et al.
Molecular Cell, 2014
CtIP-mediated resection is essential for viability and can operate independently of BRCA1.
Polato F et al.
The Journal of Experimental Medicine, 2014
FANCD2 and CtIP cooperate to repair DNA interstrand crosslinks.
Murina O et al.
Cell Reports, 2014
CtIP is required for DNA damage-dependent induction of P21.
Liu B et al.
Cell Cycle (georgetown, Tex.), 2014
The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression.
Reczek CR et al.
The Journal of Cell Biology, 2013
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Escribano-Díaz C et al.
Molecular Cell, 2013
The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair.
Wang H et al.
Plos Genetics, 2013
CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts.
Ramírez-Lugo JS et al.
Cell Cycle (georgetown, Tex.), 2011
DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints.
You Z et al.
Trends in Cell Biology, 2010
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.
Yun MH et al.
Nature, 2009
Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.
Chen L et al.
The Journal of Biological Chemistry, 2008
BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP.
Yu X et al.
Genes & Development, 2006
Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature.
Furuta S et al.
Cancer Cell, 2006
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography.
Thompson LH
Mutation Research, 0