Varaico: Literature-Extracted Genetic Variants

Gene:RBM39
Variant:p.G268V
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RBM39

NM_184234.3:p.G268V

Associated Papers

Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor.

Jablonowski C et al.

Biorxiv : the Preprint Server for Biology, 2023

Arginine reprograms metabolism in liver cancer via RBM39.

Mossmann D et al.

Cell, 2023

Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models.

Singh S et al.

Science Advances, 2021

Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15.

Faust TB et al.

Nature Chemical Biology, 2020

Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15.

Ting TC et al.

Cell Reports, 2019

Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia.

Wang E et al.

Cancer Cell, 2019

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

Han T et al.

Science (new York, N.y.), 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."