Associated Papers
Autosomal-dominant Roquin-1 immunodeficiency and hyperinflammation.
Nahum A et al.
The Journal of Allergy and Clinical Immunology, 2025
Junction of the redox dynamic, orchestra of signaling, and altered metabolism in regulation of T- cell lymphoma.
Singh S et al.
Frontiers in Oncology, 2023
Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.
Behrens G et al.
Nature Immunology, 2021
A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation.
Tavernier SJ et al.
Nature Communications, 2019
How T cells go rogue in the absence of Roquins.
Akef A et al.
Non-coding Rna Investigation, 2018
Regnase-1 and Roquin Nonredundantly Regulate Th1 Differentiation Causing Cardiac Inflammation and Fibrosis.
Cui X et al.
Journal of Immunology (baltimore, Md. : 1950), 2017
ROQUIN signalling pathways in innate and adaptive immunity.
Athanasopoulos V et al.
European Journal of Immunology, 2016
Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
Janowski R et al.
Nature Communications, 2016
Molecular Pathogenesis of Peripheral T Cell Lymphoma.
Sakata-Yanagimoto M et al.
Current Hematologic Malignancy Reports, 2015
New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.
Zhang Q et al.
Scientific Reports, 2015
Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis.
Srivastava M et al.
Nature Communications, 2015
A role for IL-10 in the transcriptional regulation of Roquin-1.
Schaefer JS et al.
Gene, 2014
A complex genomic abnormality found in a patient with antithrombin deficiency and autoimmune disease-like symptoms.
Kato I et al.
International Journal of Hematology, 2014
The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA.
Tan D et al.
Nature Structural & Molecular Biology, 2014
The lupus phenotype in B6.NZBc1 congenic mice reflects interactions between multiple susceptibility loci and a suppressor locus.
Cheung YH et al.
Genes and Immunity, 2011
Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA.
Yu D et al.
Nature, 2007