Varaico: Literature-Extracted Genetic Variants

Gene:REL
Variant:p.S471N
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REL

NM_001291746.2:p.S471N

Associated Papers

Roles of c-Rel signalling in inflammation and disease.

Fullard N et al.

The International Journal of Biochemistry & Cell Biology, 2012

An optimal range of transcription potency is necessary for efficient cell transformation by c-Rel to ensure optimal nuclear localization and gene-specific activation.

Fan Y et al.

Oncogene, 2007

NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity.

Sánchez-Valdepeñas C et al.

Journal of Immunology (baltimore, Md. : 1950), 2006

Mutations of tumor necrosis factor alpha-responsive serine residues within the C-terminal transactivation domain of human transcription factor REL enhance its in vitro transforming ability.

Starczynowski DT et al.

Oncogene, 2005

Tumor necrosis factor-alpha activation of NF-kappa B requires the phosphorylation of Ser-471 in the transactivation domain of c-Rel.

Martin AG et al.

The Journal of Biological Chemistry, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."