Associated Papers
The cirrhotic liver is depleted of docosahexaenoic acid (DHA), a key modulator of NF-κB and TGFβ pathways in hepatic stellate cells.
Enguita M et al.
Cell Death & Disease, 2019
NF-κB regulates neuronal ankyrin-G via a negative feedback loop.
König HG et al.
Scientific Reports, 2017
A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
Nilsen NJ et al.
The Journal of Biological Chemistry, 2015
Thyroid peroxidase gene expression is induced by lipopolysaccharide involving nuclear factor (NF)-κB p65 subunit phosphorylation.
Nazar M et al.
Endocrinology, 2012
microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion.
Dey N et al.
Plos One, 2012
Thr435 phosphorylation regulates RelA (p65) NF-kappaB subunit transactivation.
O'Shea JM et al.
The Biochemical Journal, 2010
GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA.
Mao X et al.
Genes & Development, 2009
Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity.
Starczynowski DT et al.
Oncogene, 2007
Suppression of p65 phosphorylation coincides with inhibition of IkappaBalpha polyubiquitination and degradation.
Hu J et al.
Molecular Carcinogenesis, 2005
Phosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway.
Sasaki CY et al.
The Journal of Biological Chemistry, 2005
Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide.
Doyle SL et al.
The Journal of Biological Chemistry, 2005
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription.
Buss H et al.
The Journal of Biological Chemistry, 2004
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