Varaico: Literature-Extracted Genetic Variants

Gene:RELA
Variant:p.T505A
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RELA

NM_021975.4:p.T505A

Associated Papers

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance.

Hunter JE et al.

The Biochemical Journal, 2022

36240065 (PubMed )
Supplement: BCJ-479-2087-s1.pdf

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway.

Hunter JE et al.

The Biochemical Journal, 2022

A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer.

Moles A et al.

Oncogene, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."