Varaico: Literature-Extracted Genetic Variants

Gene:RELN
Variant:p.H3447R
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RELN

NM_005045.4:p.H3447R

Associated Papers

Genetic contributions to Alzheimer's disease and frontotemporal dementia in admixed Latin American populations.

Acosta-Uribe J et al.

Npj Dementia, 2026

N-Sulfated Heparan Sulfate Promotes Reelin Signaling as a Co-receptor.

Pan L et al.

Journal of the American Chemical Society, 2025

Protein aggregation in neurodegenerative diseases.

Wang J et al.

Chinese Medical Journal, 2025

Novel differentially expressed genes and multiple biological pathways for Alzheimer's disease identified in brain tissue from African American donors.

Logue MW et al.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2025

Apolipoprotein E in Alzheimer's disease: molecular insights and therapeutic opportunities.

Belaidi AA et al.

Molecular Neurodegeneration, 2025

Evaluating pathogenicity of variants of unknown significance in APP, PSEN1, and PSEN2.

Marsh JA et al.

Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics, 2025

Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia.

Llibre-Guerra JJ et al.

Nature Medicine, 2025

Protective Genes Against Alzheimer's Disease: Case Review and Therapeutic Implications.

Hossain N et al.

Dementia and Neurocognitive Disorders, 2025

The impact of rare genetic variants on Alzheimer disease.

De Deyn L et al.

Nature Reviews. Neurology, 2025

Investigating the Aβ and tau pathology in autosomal dominant Alzheimer's disease: insights from hybrid PET/MRI and network mapping.

Zhou Z et al.

Alzheimer's Research & Therapy, 2025

The Spectrum of Genetic Risk in Alzheimer Disease.

Karagas N et al.

Neurology. Genetics, 2025

REELIN-COLBOS (H3447R) in Colombian oldest-old individuals, a case series.

Vasquez D et al.

Sciencebank, 2025

Effects of Angiotensin-I-Converting Enzyme (ACE) Mutations Associated with Alzheimer's Disease on Blood ACE Phenotype.

Kryukova OV et al.

Biomedicines, 2024

TREM2 on microglia cell surface binds to and forms functional binary complexes with heparan sulfate modified with 6-O-sulfation and iduronic acid.

McMillan IO et al.

The Journal of Biological Chemistry, 2024

Reelin links Apolipoprotein E4, Tau, and Amyloid-β in Alzheimer's disease.

Yi LX et al.

Ageing Research Reviews, 2024

The Role of RIN3 Gene in Alzheimer's Disease Pathogenesis: a Comprehensive Review.

Meshref M et al.

Molecular Neurobiology, 2024

A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimer's Disease.

Jin M et al.

Biorxiv : the Preprint Server for Biology, 2024

Reelin Signaling in Neurodevelopmental Disorders and Neurodegenerative Diseases.

Joly-Amado A et al.

Brain Sciences, 2023

Search Strategies for Alzheimer Protector Genes.

Kosik KS

Annals of Neurology, 2023

Resistant and Resilient mutations in protection against familial Alzheimer's disease: learning from nature.

Sepulveda-Falla D

Molecular Neurodegeneration, 2023

Genetic protection from early-onset familial Alzheimer's disease.

Kriebs A

Nature Aging, 2023

Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man.

Lopera F et al.

Nature Medicine, 2023

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