Associated Papers
Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum.
Panda G et al.
Frontiers in Pharmacology, 2022
Roles of the RET Proto-oncogene in Cancer and Development.
Takahashi M et al.
Jma Journal, 2020
Mutational landscape and genetic signatures of cell-free DNA in tumour-induced osteomalacia.
Wu N et al.
Journal of Cellular and Molecular Medicine, 2020
Sequence characterization of RET in 117 Chinese Hirschsprung disease families identifies a large burden of de novo and parental mosaic mutations.
Jiang Q et al.
Orphanet Journal of Rare Diseases, 2019
Mammal-restricted elements predispose human RET to folding impairment by HSCR mutations.
Kjaer S et al.
Nature Structural & Molecular Biology, 2010
Genetics of Hirschsprung disease and anorectal malformations.
Mundt E et al.
Seminars in Pediatric Surgery, 2010
RET(MEN 2B) is active in the endoplasmic reticulum before reaching the cell surface.
Runeberg-Roos P et al.
Oncogene, 2007
[Molecular biology, basic research and diagnosis of Hirschsprung's disease].
Martucciello G et al.
Der Pathologe, 2007
RET receptor signaling: dysfunction in thyroid cancer and Hirschsprung's disease.
Asai N et al.
Pathology International, 2006
Identification of a surface for binding to the GDNF-GFR alpha 1 complex in the first cadherin-like domain of RET.
Kjaer S et al.
The Journal of Biological Chemistry, 2003
A new therapeutic approach in medullary thyroid cancer treatment: inhibition of oncogenic RET signaling by adenoviral vector-mediated expression of a dominant-negative RET mutant.
Drosten M et al.
Surgery, 2002
Molecular modeling of the extracellular domain of the RET receptor tyrosine kinase reveals multiple cadherin-like domains and a calcium-binding site.
Anders J et al.
The Journal of Biological Chemistry, 2001
Genetic disorders of calcium and phosphorus metabolism.
Root AW
Critical Reviews in Clinical Laboratory Sciences, 2000
A human model for multigenic inheritance: phenotypic expression in Hirschsprung disease requires both the RET gene and a new 9q31 locus.
Bolk S et al.
Proceedings of the National Academy of Sciences of the United States of America, 2000
Different mutations of the RET gene cause different human tumoral diseases.
Santoro M et al.
Biochimie, 1999
Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease.
Carlomagno F et al.
Endocrinology, 1998
Molecular biology of the MEN2 gene.
Santoro M et al.
Journal of Internal Medicine, 1998
The genetics of anorectal malformations: a complex matter.
Lerone M et al.
Seminars in Pediatric Surgery, 1997
Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and hirschsprung disease.
Eng C et al.
Human Mutation, 1997
Mechanism of ret dysfunction by Hirschsprung mutations affecting its extracellular domain.
Iwashita T et al.
Human Molecular Genetics, 1996
RET mutations in multiple endocrine neoplasia type 2 and Hirschsprung disease.
Reynolds LF et al.
Current Opinion in Pediatrics, 1995
Diversity of RET proto-oncogene mutations in familial and sporadic Hirschsprung disease.
Attié T et al.
Human Molecular Genetics, 1995
Long segment and short segment familial Hirschsprung's disease: variable clinical expression at the RET locus.
Edery P et al.
Journal of Medical Genetics, 1994
[Mutations of RET proto-oncogene in Hirschsprung disease].
Lyonnet S et al.
Comptes Rendus De L'academie Des Sciences. Serie Iii, Sciences De La Vie, 1994