Associated Papers
Pan-Cancer Exome-wide analysis of germline mutational patterns and pathways.
Alnaqbi H et al.
Scientific Reports, 2025
An integrative pan cancer analysis of RET aberrations and their potential clinical implications.
Zhou L et al.
Scientific Reports, 2022
Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum.
Panda G et al.
Frontiers in Pharmacology, 2022
Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.
Yin XQ et al.
Frontiers in Oncology, 2022
HER2 Amplification in Advanced NSCLC Patients After Progression on EGFR-TKI and Clinical Response to EGFR-TKI Plus Pyrotinib Combination Therapy.
Gan J et al.
Oncotargets and Therapy, 2021
Sequence characterization of RET in 117 Chinese Hirschsprung disease families identifies a large burden of de novo and parental mosaic mutations.
Jiang Q et al.
Orphanet Journal of Rare Diseases, 2019
Functional Studies on Novel RET Mutations and Their Implications for Genetic Counseling for Hirschsprung Disease.
Wang H et al.
Frontiers in Genetics, 2019
RET somatic mutations are underrecognized in Hirschsprung disease.
Jiang Q et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2018
Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing.
Oliveira DM et al.
Oncotarget, 2018
Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene.
Mendes Oliveira D et al.
Journal of Experimental & Clinical Cancer Research : Cr, 2018
Receptor tyrosine kinase mutations in developmental syndromes and cancer: two sides of the same coin.
McDonell LM et al.
Human Molecular Genetics, 2015
Comprehensive assessment of the disputed RET Y791F variant shows no association with medullary thyroid carcinoma susceptibility.
Toledo RA et al.
Endocrine-related Cancer, 2015
Genotyping analysis of 3 RET polymorphisms demonstrates low somatic mutation rate in Chinese Hirschsprung disease patients.
Zhang Z et al.
International Journal of Clinical and Experimental Pathology, 2015
Consensus: a framework for evaluation of uncertain gene variants in laboratory test reporting.
Crockett DK et al.
Genome Medicine, 2012
Modification of multiple endocrine neoplasia 2A phenotype by cell membrane proximity of RET mutations in exon 10.
Machens A et al.
Endocrine-related Cancer, 2009
[Molecular biology, basic research and diagnosis of Hirschsprung's disease].
Martucciello G et al.
Der Pathologe, 2007
Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations.
Kjaer S et al.
Oncogene, 2006
Polymerase chain reaction-single strand conformational polymorphism analysis of rearranged during transfection proto-oncogene in Chinese familial Hirschsprung's disease.
Guan T et al.
World Journal of Gastroenterology, 2005
Segregation at three loci explains familial and population risk in Hirschsprung disease.
Gabriel SB et al.
Nature Genetics, 2002
Molecular modeling of the extracellular domain of the RET receptor tyrosine kinase reveals multiple cadherin-like domains and a calcium-binding site.
Anders J et al.
The Journal of Biological Chemistry, 2001
Familial form of hirschsprung disease: nucleotide sequence studies reveal point mutations in the RET proto-oncogene in two of six families but not in other candidate genes.
Munnes M et al.
American Journal of Medical Genetics, 2000
A human model for multigenic inheritance: phenotypic expression in Hirschsprung disease requires both the RET gene and a new 9q31 locus.
Bolk S et al.
Proceedings of the National Academy of Sciences of the United States of America, 2000