Varaico: Literature-Extracted Genetic Variants

Gene:RET
Variant:p.G423G
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RET

NM_020975.6:p.G423G

Associated Papers

Novel therapeutic strategies for rare mutations in non-small cell lung cancer.

Gou Q et al.

Scientific Reports, 2024

EML4-ALK biology and drug resistance in non-small cell lung cancer: a new phase of discoveries.

Elshatlawy M et al.

Molecular Oncology, 2023

The return of RET GateKeeper mutations? an in-silico exploratory analysis of potential resistance mechanisms to novel RET macrocyclic inhibitor TPX-0046.

Repetto M et al.

Investigational New Drugs, 2022

Utility of the Ba/F3 cell system for exploring on-target mechanisms of resistance to targeted therapies for lung cancer.

Koga T et al.

Cancer Science, 2022

Will the clinical development of 4th-generation "double mutant active" ALK TKIs (TPX-0131 and NVL-655) change the future treatment paradigm of ALK+ NSCLC?

Ou SI et al.

Translational Oncology, 2021

NGS-based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment.

Sánchez-Herrero E et al.

Molecular Oncology, 2021

34058070 (PubMed )
Supplement: MOL2-15-2363-s001.docx

Computational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation.

Patil K et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021

Targeting anaplastic lymphoma kinase in neuroblastoma.

Umapathy G et al.

Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 2019

Resistance to molecularly targeted therapy in non-small-cell lung cancer.

Asao T et al.

Respiratory Investigation, 2019

The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models.

Zhang S et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016

27780853 (PubMed )
Supplement: 10780432ccr160569-sup-163226_2_supp_3574910_tdyq9n.pdf
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