Varaico: Literature-Extracted Genetic Variants

Gene:RET
Variant:p.C630G
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RET

NM_020975.6:p.C630G

Associated Papers

Patient-Derived in Vitro Models Reveal Insights into Medullary Thyroid Cancer Microenvironment and Resistance to Tyrosine Kinase Inhibitors.

Grassi ES et al.

Thyroid : Official Journal of the American Thyroid Association, 2026

A novel multimodal diagnostic framework integrating hyperspectral imaging and deep learning for predicting RET gene mutations in medullary thyroid carcinoma.

Yang Z et al.

Computer Methods and Programs in Biomedicine, 2026

Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma.

Zhou Y et al.

Nature Communications, 2026

41535264 (PubMed )
Supplement: 41467_2025_67533_MOESM3_ESM.xlsx › Sheet1

Landscape of Phenotype-Genotype Correlations in Romanian Patients with Medullary Thyroid Carcinoma.

Stanescu LS et al.

Cancers, 2025

Molecular profiling of sporadic medullary thyroid carcinomas - a next-generation sequencing-based study.

Altinay S et al.

Polish Journal of Pathology : Official Journal of the Polish Society of Pathologists, 2025

Integrated proteogenomic characterization of medullary thyroid carcinoma.

Shi X et al.

Cell Discovery, 2022

36344509 (PubMed )
Supplement: 41421_2022_479_MOESM4_ESM.xlsx › Somatic_mutations

Pre- and Post-operative Circulating Tumoral DNA in Patients With Medullary Thyroid Carcinoma.

Ciampi R et al.

The Journal of Clinical Endocrinology and Metabolism, 2022

The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers.

Rosen EY et al.

Nature Communications, 2022

35304457 (PubMed )
Supplement: 41467_2022_28848_MOESM1_ESM.pdf

Evaluation of grade in a genotyped cohort of sporadic medullary thyroid carcinomas.

Najdawi F et al.

Histopathology, 2021

Role of tissue and circulating microRNAs and DNA as biomarkers in medullary thyroid cancer.

Chiacchiarini M et al.

Pharmacology & Therapeutics, 2021

Differences in the transcriptome of medullary thyroid cancer regarding the status and type of RET gene mutations.

Oczko-Wojciechowska M et al.

Scientific Reports, 2017

28181547 (PubMed )
Supplement: srep42074-s1.pdf

The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes.

Pagan M et al.

Bmc Bioinformatics, 2016

26818556 (PubMed )
Supplement: 12859_2015_849_MOESM3_ESM.pdf

Comprehensive assessment of the disputed RET Y791F variant shows no association with medullary thyroid carcinoma susceptibility.

Toledo RA et al.

Endocrine-related Cancer, 2015

25425582 (PubMed )
Supplement: supp_ERC-14-0491_Supplementary_table_2.xlsx › Sheet1

The prevalence of somatic RAS mutations in medullary thyroid cancer - a Polish population study.

Oczko-Wojciechowska M et al.

Endokrynologia Polska, 2015

Correlation of RET somatic mutations with clinicopathological features in sporadic medullary thyroid carcinomas.

Moura MM et al.

British Journal of Cancer, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."