Varaico: Literature-Extracted Genetic Variants

Gene:RET
Variant:p.C634*
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RET

NM_020975.6:p.C634*

Associated Papers

Calcitonin Thresholds for Prediction of Medullary Thyroid Carcinoma and its Clinical Response in MEN2A Gene Carriers.

Prete A et al.

The Journal of Clinical Endocrinology and Metabolism, 2026

Four decades of the RET gene: From discovery to tumor-agnostic therapy.

Takahashi M

Journal of the Formosan Medical Association = Taiwan Yi Zhi, 2025

Approach to the Patient: Hereditary Medullary Thyroid Carcinoma.

Shariq OA et al.

The Journal of Clinical Endocrinology and Metabolism, 2025

Kinome profiling reveals pathogenic variant specific protein signalling networks in MEN2 children with Medullary Thyroid Cancer.

Rix B et al.

Npj Precision Oncology, 2025

Genomic testing for RET in the clinic: UK and global perspective.

Izatt L

Endocrine-related Cancer, 2025

Efficacy and Safety of Selective RET Inhibitors in Patients with Advanced Hereditary Medullary Thyroid Carcinoma.

Hamidi S et al.

Thyroid : Official Journal of the American Thyroid Association, 2025

Pediatric Medullary Thyroid Carcinoma: Clinical Presentations and Long-Term Outcomes in 144 Patients Over 6 Decades.

Hensley SG et al.

The Journal of Clinical Endocrinology and Metabolism, 2024

Patterns of Treatment Failure After Selective Rearranged During Transfection (RET) Inhibitors in Patients With Metastatic Medullary Thyroid Carcinoma.

Hadoux J et al.

Jco Precision Oncology, 2023

RET-Altered Cancers-A Tumor-Agnostic Review of Biology, Diagnosis and Targeted Therapy Activity.

Desilets A et al.

Cancers, 2023

GLOBAL ENDOCRINOLOGY: Geographical variation in the profile of RET variants in patients with medullary thyroid cancer: a comprehensive review.

Maciel RMB et al.

European Journal of Endocrinology, 2021

Active Surveillance in RET Gene Carriers Belonging to Families with Multiple Endocrine Neoplasia.

Prete A et al.

Cancers, 2021

Exceptionality of Distant Metastasis in Node-Negative Hereditary and Sporadic Medullary Thyroid Cancer: Lessons Learned.

Machens A et al.

The Journal of Clinical Endocrinology and Metabolism, 2021

Lymph node metastasis in hereditary medullary thyroid cancer is independent of the underlying RET germline mutation.

Machens A et al.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021

ESMO recommendations on the standard methods to detect RET fusions and mutations in daily practice and clinical research.

Belli C et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2021

Pralsetinib: First Approval.

Markham A

Drugs, 2020

RET Receptor Tyrosine Kinase: Role in Neurodegeneration, Obesity, and Cancer.

Mahato AK et al.

International Journal of Molecular Sciences, 2020

Long-Term Oncologic Outcomes After Curative Resection of Familial Medullary Thyroid Carcinoma.

Spanheimer PM et al.

Annals of Surgical Oncology, 2019

Twenty-Five Years Experience on RET Genetic Screening on Hereditary MTC: An Update on The Prevalence of Germline RET Mutations.

Elisei R et al.

Genes, 2019

Long-term outcome after DNA-based prophylactic neck surgery in children at risk of hereditary medullary thyroid cancer.

Machens A et al.

Best Practice & Research. Clinical Endocrinology & Metabolism, 2019

Mice conditionally expressing RET(C618F) mutation display C cell hyperplasia and hyperganglionosis of the enteric nervous system.

Okamoto M et al.

Genesis (new York, N.y. : 2000), 2019

Genotype-specific progression of hereditary medullary thyroid cancer.

Machens A et al.

Human Mutation, 2018

Central role of RET in thyroid cancer.

Santoro M et al.

Cold Spring Harbor Perspectives in Biology, 2013

The role of the ret proto-oncogene in human disease.

Takahashi M

Nagoya Journal of Medical Science, 1997

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