Varaico: Literature-Extracted Genetic Variants

Gene:RET
Variant:p.K758R
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RET

NM_020975.6:p.K758R

Associated Papers

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

Yadav L et al.

Iscience, 2020

Functional characterization of a novel FGFR1OP-RET rearrangement in hematopoietic malignancies.

Bossi D et al.

Molecular Oncology, 2014

RET is a potential tumor suppressor gene in colorectal cancer.

Luo Y et al.

Oncogene, 2013

RET modulates cell adhesion via its cleavage by caspase in sympathetic neurons.

Cabrera JR et al.

The Journal of Biological Chemistry, 2011

The RET51/FKBP52 complex and its involvement in Parkinson disease.

Fusco D et al.

Human Molecular Genetics, 2010

The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability.

Vargiolu M et al.

The Journal of Clinical Endocrinology and Metabolism, 2009

A novel activating mutation in the RET tyrosine kinase domain mediates neoplastic transformation.

Cranston A et al.

Molecular Endocrinology (baltimore, Md.), 2006

Biological effects of the dual phenotypic Janus mutation of ret cosegregating with both multiple endocrine neoplasia type 2 and Hirschsprung's disease.

Arighi E et al.

Molecular Endocrinology (baltimore, Md.), 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."