Associated Papers
RET Gene Alterations in Clinical Practice: A Comprehensive Review and Database Update.
Ricciardi Tenore C et al.
Genes, 2025
The RET gene encodes RET protein, which triggers intracellular signaling pathways for enteric neurogenesis, and RET mutation results in Hirschsprung's disease.
Bhattarai C et al.
Aims Neuroscience, 2022
Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum.
Panda G et al.
Frontiers in Pharmacology, 2022
Roles of the RET Proto-oncogene in Cancer and Development.
Takahashi M et al.
Jma Journal, 2020
In silico profiling and structural insights of missense mutations in RET protein kinase domain by molecular dynamics and docking approach.
George Priya Doss C et al.
Molecular Biosystems, 2014
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.
Ryu GM et al.
Nucleic Acids Research, 2009
[Molecular biology, basic research and diagnosis of Hirschsprung's disease].
Martucciello G et al.
Der Pathologe, 2007
Structure and chemical inhibition of the RET tyrosine kinase domain.
Knowles PP et al.
The Journal of Biological Chemistry, 2006
RET receptor signaling: dysfunction in thyroid cancer and Hirschsprung's disease.
Asai N et al.
Pathology International, 2006
Haplotypes of the human RET proto-oncogene associated with Hirschsprung disease in the Italian population derive from a single ancestral combination of alleles.
Lantieri F et al.
Annals of Human Genetics, 2006
Biological effects of the dual phenotypic Janus mutation of ret cosegregating with both multiple endocrine neoplasia type 2 and Hirschsprung's disease.
Arighi E et al.
Molecular Endocrinology (baltimore, Md.), 2004
Functional analysis of RET with Hirschsprung mutations affecting its kinase domain.
Iwashita T et al.
Gastroenterology, 2001
Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and hirschsprung disease.
Eng C et al.
Human Mutation, 1997
Frequency of RET mutations in long- and short-segment Hirschsprung disease.
Seri M et al.
Human Mutation, 1997
RET mutations in multiple endocrine neoplasia type 2 and Hirschsprung disease.
Reynolds LF et al.
Current Opinion in Pediatrics, 1995
Loss of function effect of RET mutations causing Hirschsprung disease.
Pasini B et al.
Nature Genetics, 1995
[Identification of mutation of RET proto-oncogene in Hirschsprung disease].
Attié T et al.
Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales, 1994