Varaico: Literature-Extracted Genetic Variants

Gene:RET
Variant:p.P766S
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RET

NM_020975.6:p.P766S

Associated Papers

Comprehensive assessment of the disputed RET Y791F variant shows no association with medullary thyroid carcinoma susceptibility.

Toledo RA et al.

Endocrine-related Cancer, 2015

25425582 (PubMed )
Supplement: supp_ERC-14-0491_Supplementary_table_2.xlsx › Sheet1

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

Beyond RET: potential therapeutic approaches for advanced and metastatic medullary thyroid carcinoma.

Santarpia L et al.

Journal of Internal Medicine, 2009

Dysregulated RET signaling in thyroid cancer.

Castellone MD et al.

Endocrinology and Metabolism Clinics of North America, 2008

Structure and chemical inhibition of the RET tyrosine kinase domain.

Knowles PP et al.

The Journal of Biological Chemistry, 2006

Minireview: RET: normal and abnormal functions.

Santoro M et al.

Endocrinology, 2004

Dysfunction of the RET receptor in human cancer.

Santoro M et al.

Cellular and Molecular Life Sciences : Cmls, 2004

Somatic mutations in RET exons 12 and 15 in sporadic medullary thyroid carcinomas: different spectrum of mutations in sporadic type from hereditary type.

Uchino S et al.

Japanese Journal of Cancer Research : Gann, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."