Associated Papers
Calcitonin Thresholds for Prediction of Medullary Thyroid Carcinoma and its Clinical Response in MEN2A Gene Carriers.
Prete A et al.
The Journal of Clinical Endocrinology and Metabolism, 2026
Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma.
Zhou Y et al.
Nature Communications, 2026
Medullary thyroid carcinoma exclusively associated with a homozygous RET V778I pathogenic variant: a case report with review of literature.
Kihara M et al.
Endocrine Journal, 2026
Rare cases in two Chinese MEN2A families with RET C634Y germline mutation-a homozygous female patient and heterozygous identical twins: a systematic review of literature.
Qi XP et al.
Frontiers in Endocrinology, 2026
Decoding genomic rearrangements for cancer driver discovery.
Seo E et al.
Molecules and Cells, 2025
Genetic profiles of oligometastatic non-small-cell lung cancer and corresponding brain metastases.
Werner RS et al.
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery, 2024
Accelerated MEN2A in homozygous RET carriers in the context of consanguinity.
Machens A et al.
European Journal of Endocrinology, 2024
Looking for RET alterations in thyroid cancer: clinical relevance, methodology and timing.
Elisei R et al.
Endocrine, 2023
Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis.
Tabata J et al.
Cancer Research, 2022
GLOBAL ENDOCRINOLOGY: Geographical variation in the profile of RET variants in patients with medullary thyroid cancer: a comprehensive review.
Maciel RMB et al.
European Journal of Endocrinology, 2021
Comparative Analysis of Genetic Alterations, HPV-Status, and PD-L1 Expression in Neuroendocrine Carcinomas of the Cervix.
Takayanagi D et al.
Cancers, 2021
A Narrative Review of Genetic Alterations in Primary Thyroid Epithelial Cancer.
Romei C et al.
International Journal of Molecular Sciences, 2021
Twenty-Five Years Experience on RET Genetic Screening on Hereditary MTC: An Update on The Prevalence of Germline RET Mutations.
Elisei R et al.
Genes, 2019
Long-term outcome after DNA-based prophylactic neck surgery in children at risk of hereditary medullary thyroid cancer.
Machens A et al.
Best Practice & Research. Clinical Endocrinology & Metabolism, 2019
Expression and copy number gains of the RET gene in 631 early and mid stage non-small cell lung cancer cases.
Tan L et al.
Thoracic Cancer, 2018
RET mutation heterogeneity in primary advanced medullary thyroid cancers and their metastases.
Romei C et al.
Oncotarget, 2018
A pioneering RET genetic screening study in the State of Ceará, Brazil, evaluating patients with medullary thyroid cancer and at-risk relatives: experience with 247 individuals.
Martins-Costa MC et al.
Archives of Endocrinology and Metabolism, 2018
Nationwide French Study of RET Variants Detected from 2003 to 2013 Suggests a Possible Influence of Polymorphisms as Modifiers.
Lebeault M et al.
Thyroid : Official Journal of the American Thyroid Association, 2017
Risk Profile of the RET A883F Germline Mutation: An International Collaborative Study.
Mathiesen JS et al.
The Journal of Clinical Endocrinology and Metabolism, 2017
The RET E616Q Variant is a Gain of Function Mutation Present in a Family with Features of Multiple Endocrine Neoplasia 2A.
Grey W et al.
Endocrine Pathology, 2017
Management of hereditary medullary thyroid carcinoma.
Pappa T et al.
Endocrine, 2016
A comprehensive overview of the role of the RET proto-oncogene in thyroid carcinoma.
Romei C et al.
Nature Reviews. Endocrinology, 2016
The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes.
Pagan M et al.
Bmc Bioinformatics, 2016
Elevated level of serum carbohydrate antigen 19.9 as predictor of mortality in patients with advanced medullary thyroid cancer.
Elisei R et al.
European Journal of Endocrinology, 2015
Possible Impact of RET Polymorphism and Its Haplotypic Association Modulates the Susceptibility to Thyroid Cancer.
Khan MS et al.
Journal of Cellular Biochemistry, 2015
Twenty years of lesson learning: how does the RET genetic screening test impact the clinical management of medullary thyroid cancer?
Romei C et al.
Clinical Endocrinology, 2015
Comprehensive assessment of the disputed RET Y791F variant shows no association with medullary thyroid carcinoma susceptibility.
Toledo RA et al.
Endocrine-related Cancer, 2015
Novel RET mutations in macedonian patients with medullary thyroid carcinoma: genotype-phenotype correlations.
Jovanovic R et al.
Prilozi (makedonska Akademija Na Naukite I Umetnostite. Oddelenie Za Medicinski Nauki), 2015
The value of genetic screening in medullary thyroid cancer.
Pappa T et al.
Expert Review of Endocrinology & Metabolism, 2014
Novel tandem germline RET proto-oncogene mutations in a patient with multiple endocrine neoplasia type 2B: report of a case and a literature review of tandem RET mutations with in silico analysis.
Nakao KT et al.
Head & Neck, 2013
Molecular epidemiology of multiple endocrine neoplasia 2: implications for RET screening in the new millenium.
Machens A et al.
European Journal of Endocrinology, 2013
The timing of total thyroidectomy in RET gene mutation carriers could be personalized and safely planned on the basis of serum calcitonin: 18 years experience at one single center.
Elisei R et al.
The Journal of Clinical Endocrinology and Metabolism, 2012
Chromosome 10 and RET gene copy number alterations in hereditary and sporadic Medullary Thyroid Carcinoma.
Ciampi R et al.
Molecular and Cellular Endocrinology, 2012
In silico and in vitro analysis of rare germline allelic variants of RET oncogene associated with medullary thyroid cancer.
Cosci B et al.
Endocrine-related Cancer, 2011
Multiple endocrine neoplasia type 2 syndromes (MEN 2): results from the ItaMEN network analysis on the prevalence of different genotypes and phenotypes.
Romei C et al.
European Journal of Endocrinology, 2010
Medullary thyroid cancer: RET testing of an archival material.
Godballe C et al.
European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-rhino-laryngological Societies (eufos) : Affiliated With the German Society for Oto-rhino-laryngology - Head and Neck Surgery, 2010
Multiple endocrine neoplasia type 2 RET protooncogene database: repository of MEN2-associated RET sequence variation and reference for genotype/phenotype correlations.
Margraf RL et al.
Human Mutation, 2009
Prognostic significance of somatic RET oncogene mutations in sporadic medullary thyroid cancer: a 10-year follow-up study.
Elisei R et al.
The Journal of Clinical Endocrinology and Metabolism, 2008
RET genetic screening in patients with medullary thyroid cancer and their relatives: experience with 807 individuals at one center.
Elisei R et al.
The Journal of Clinical Endocrinology and Metabolism, 2007
RET signaling in endocrine tumors: delving deeper into molecular mechanisms.
Lai AZ et al.
Endocrine Pathology, 2007
A rare RET gene exon 8 mutation is found in two Greek kindreds with familial medullary thyroid carcinoma: implications for screening.
Kaldrymides P et al.
Clinical Endocrinology, 2006
Multiple endocrine neoplasia type 2 and the RET protooncogene: from bedside to bench to bedside.
Machens A et al.
Molecular and Cellular Endocrinology, 2006
Hereditary hormone excess: genes, molecular pathways, and syndromes.
Marx SJ et al.
Endocrine Reviews, 2005
Germline homozygous mutations at codon 804 in the RET protooncogene in medullary thyroid carcinoma/multiple endocrine neoplasia type 2A patients.
Lesueur F et al.
The Journal of Clinical Endocrinology and Metabolism, 2005
RET proto-oncogene: a review and update of genotype-phenotype correlations in hereditary medullary thyroid cancer and associated endocrine tumors.
Kouvaraki MA et al.
Thyroid : Official Journal of the American Thyroid Association, 2005
Molecular genetics of multiple endocrine neoplasia types 1 and 2.
Marx SJ
Nature Reviews. Cancer, 2005
Identification of a novel point mutation in the RET gene (Ala883Thr), which is associated with medullary thyroid carcinoma phenotype only in homozygous condition.
Elisei R et al.
The Journal of Clinical Endocrinology and Metabolism, 2004