Varaico: Literature-Extracted Genetic Variants

Gene:RET
Variant:p.D898Y
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RET

NM_020975.6:p.D898Y

Associated Papers

Primary resistance to selpercatinib in a patient with advanced medullary thyroid cancer.

Pitoia F et al.

Endocrine, 2024

Personalized Medicine in Medullary Thyroid Carcinoma: A Broad Review of Emerging Treatments.

Martins RS et al.

Journal of Personalized Medicine, 2023

Update on C-Cell Neuroendocrine Neoplasm: Prognostic and Predictive Histopathologic and Molecular Features of Medullary Thyroid Carcinoma.

Jung CK et al.

Endocrine Pathology, 2023

Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis.

Tabata J et al.

Cancer Research, 2022

36166639 (PubMed )
Supplement: can-22-0834_supplementary_table_s1_suppst1.xlsx › Supplementary_Table_S1

The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers.

Rosen EY et al.

Nature Communications, 2022

Characteristics of germline mutations in Korean patients with pheochromocytoma/paraganglioma.

Kim JH et al.

Journal of Medical Genetics, 2022

Age-Dependent De Novo Mutations During Spermatogenesis and Their Consequences.

Cioppi F et al.

Advances in Experimental Medicine and Biology, 2019

Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.

Maher GJ et al.

Genome Research, 2018

30355600 (PubMed )
Supplement: supp_gr.239186.118_Supplemental_Table_S3.xlsx › Table_of_prioritized_calls

A Novel RET D898Y Germline Mutation in a Patient with Pheochromocytoma.

Yi JW et al.

Case Reports in Endocrinology, 2018

Bilateral Pheochromocytomas in MEN2A Syndrome: A Two-Institution Experience.

Lang BH et al.

World Journal of Surgery, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."