Associated Papers
Circulating tumor DNA profiling for non-invasive genomic analysis in Indian lung cancer patients: A real-world experience.
Jha P et al.
The Journal of Liquid Biopsy, 2025
The RET gene encodes RET protein, which triggers intracellular signaling pathways for enteric neurogenesis, and RET mutation results in Hirschsprung's disease.
Bhattarai C et al.
Aims Neuroscience, 2022
Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum.
Panda G et al.
Frontiers in Pharmacology, 2022
Comparative Analysis of Genetic Alterations, HPV-Status, and PD-L1 Expression in Neuroendocrine Carcinomas of the Cervix.
Takayanagi D et al.
Cancers, 2021
Role of tissue and circulating microRNAs and DNA as biomarkers in medullary thyroid cancer.
Chiacchiarini M et al.
Pharmacology & Therapeutics, 2021
Roles of the RET Proto-oncogene in Cancer and Development.
Takahashi M et al.
Jma Journal, 2020
Development and Analytical Validation of an Expanded Mutation Detection Panel for Next-Generation Sequencing of Thyroid Nodule Aspirates.
Ablordeppey KK et al.
The Journal of Molecular Diagnostics : Jmd, 2020
Receptor tyrosine kinase mutations in developmental syndromes and cancer: two sides of the same coin.
McDonell LM et al.
Human Molecular Genetics, 2015
Comprehensive assessment of the disputed RET Y791F variant shows no association with medullary thyroid carcinoma susceptibility.
Toledo RA et al.
Endocrine-related Cancer, 2015
[Hereditary thyroid carcinoma and its molecular diagnostics].
Dvořáková S et al.
Ceskoslovenska Patologie, 2014
Multiple functional effects of RET kinase domain sequence variants in Hirschsprung disease.
Hyndman BD et al.
Human Mutation, 2013
The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.
Stehr H et al.
Molecular Cancer, 2011
Beyond RET: potential therapeutic approaches for advanced and metastatic medullary thyroid carcinoma.
Santarpia L et al.
Journal of Internal Medicine, 2009
Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
Tang Z et al.
Oncogene, 2009
Somatic mutations in the RET proto-oncogene in sporadic medullary thyroid carcinomas.
Dvorakova S et al.
Molecular and Cellular Endocrinology, 2008
RET(MEN 2B) is active in the endoplasmic reticulum before reaching the cell surface.
Runeberg-Roos P et al.
Oncogene, 2007
[Molecular biology, basic research and diagnosis of Hirschsprung's disease].
Martucciello G et al.
Der Pathologe, 2007
[Thyroid carcinomas and Hirschsprung's disease--10-year experience with molecular genetic testing of the RET proto-oncogene].
Bendlová B et al.
Vnitrni Lekarstvi, 2006
RET receptor signaling: dysfunction in thyroid cancer and Hirschsprung's disease.
Asai N et al.
Pathology International, 2006
New multiple somatic mutations in the RET proto-oncogene associated with a sporadic medullary thyroid carcinoma.
Dvoráková S et al.
Thyroid : Official Journal of the American Thyroid Association, 2006
Homozygosity for a frequent and weakly penetrant predisposing allele at the RET locus in sporadic Hirschsprung disease.
Pelet A et al.
Journal of Medical Genetics, 2005
Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine.
Kato M et al.
Cancer Research, 2002
The pathogenesis of Hirschsprung disease.
Belknap WM
Current Opinion in Gastroenterology, 2002
Functional analysis of RET with Hirschsprung mutations affecting its kinase domain.
Iwashita T et al.
Gastroenterology, 2001
Various mechanisms cause RET-mediated signaling defects in Hirschsprung's disease.
Pelet A et al.
The Journal of Clinical Investigation, 1998
Hirschsprung's disease as a neurochristopathy.
Martucciello G
Pediatric Surgery International, 1997
Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and hirschsprung disease.
Eng C et al.
Human Mutation, 1997
RET mutations in multiple endocrine neoplasia type 2 and Hirschsprung disease.
Reynolds LF et al.
Current Opinion in Pediatrics, 1995
Diversity of RET proto-oncogene mutations in familial and sporadic Hirschsprung disease.
Attié T et al.
Human Molecular Genetics, 1995