Associated Papers
SLFN11 counteracts the RFWD3-PRIMPOL DNA damage tolerance axis to restrain gapped DNA synthesis in response to replication stress.
Coleman KE et al.
Nature Communications, 2025
41372167 (PubMed )
Supplement: 41467_2025_66068_MOESM3_ESM.pdf
Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens.
Gu S et al.
Nature Communications, 2025
E3 ligases: a ubiquitous link between DNA repair, DNA replication and human disease.
Chauhan AS et al.
The Biochemical Journal, 2024
SMARCAL1 ubiquitylation controls its association with RPA-coated ssDNA and promotes replication fork stability.
Yates M et al.
Plos Biology, 2024
Further Evidence for RFWD3 Gene Causing Fanconi Anemia Complementation Group W: Detailed Clinical Report of the Second Case in the Literature.
Kocagil S et al.
Molecular Syndromology, 2023
Implications of ubiquitination and the maintenance of replication fork stability in cancer therapy.
Xia D et al.
Bioscience Reports, 2023
RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks.
Moore CE et al.
The Journal of Cell Biology, 2023
The ubiquitin ligase RFWD3 is required for translesion DNA synthesis.
Gallina I et al.
Molecular Cell, 2021
Proteolytic control of genome integrity at the replication fork.
Rageul J et al.
Dna Repair, 2019
PCNA-mediated stabilization of E3 ligase RFWD3 at the replication fork is essential for DNA replication.
Lin YC et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018
Ubiquitylation at the Fork: Making and Breaking Chains to Complete DNA Replication.
Yates M et al.
International Journal of Molecular Sciences, 2018
Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia.
Knies K et al.
The Journal of Clinical Investigation, 2017
RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health.
Feeney L et al.
Molecular Cell, 2017
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