Varaico: Literature-Extracted Genetic Variants

Gene:RGS14
Variant:p.E92A
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RGS14

NM_006480.5:p.E92A

Associated Papers

RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways.

Shu FJ et al.

Cellular Signalling, 2010

RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock.

Cho H et al.

The Journal of Biological Chemistry, 2005

The RGS (regulator of G-protein signalling) and GoLoco domains of RGS14 co-operate to regulate Gi-mediated signalling.

Traver S et al.

The Biochemical Journal, 2004

Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons.

Squires KE et al.

The Journal of Biological Chemistry, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."