Varaico: Literature-Extracted Genetic Variants

Gene:RHD
Variant:p.K409K
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RHD

NM_016124.6:p.K409K

Associated Papers

Advancements in Blood Group Genotyping Technology and Clinical Applications.

Liu X et al.

Clinical Chemistry, 2026

Serological weak D phenotype caused by a novel RHD variant allele with a nucleotide change (c.283G>T).

Hou J et al.

Transfusion, 2026

Allelic Cataloging of RHD-RHCE Reference Sequences Using Targeted Long-Read Sequencing.

Song J et al.

Clinical Chemistry, 2025

The novel c.1227+2T>C variant in RHD results in the serological D-negative phenotype.

Lee JK et al.

Transfusion, 2025

Combining computational approaches and functional analysis for characterizing the deleterious effect of RHD gene variants on splicing in the Chinese population.

Jia S et al.

Transfusion, 2025

The need for routine detection of the Asian-type DEL allele in individuals with weak or partial D phenotypes from East and Southeast Asian populations.

Wen J et al.

Vox Sanguinis, 2025

Weak D phenotype in transfusion medicine and obstetrics: Challenges and opportunities.

Sainath PB et al.

World Journal of Experimental Medicine, 2025

Transitioning a multiethnic donor pool from serologic D-negative to molecularly RHD-negative at a hospital-based blood donor service.

Flegel WA et al.

Journal of Translational Medicine, 2025

The RhCcEe phenotype incompatibility in Chinese and presence of DEL in serologically D-, C/E+ individuals.

Xiong Y et al.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis, 2025

Single-Tube Multiplex PCR-SSP for the Detection of RHD Variant Alleles Commonly Found in Serologically D- Phenotype Individuals in a Thai Population.

Pittayabumrung O et al.

Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie, 2025

[Serological and Molecular Biological Detection of RhD Variants].

Ren DJ et al.

Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2025

A Case of Bidirectional ABO- and RhD-Incompatible Liver Transplantation in a Mongolian Patient With Asian-Type DEL.

Kang T et al.

Annals of Laboratory Medicine, 2025

Prediction of immunogenicity of Rh antigens using in silico analysis of binding to human leukocyte antigen peptide, Basic/Translational Research.

Youk HJ et al.

Plos One, 2025

A Chinese individual with DEL phenotype caused by a novel RHD allele.

Wu F et al.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis, 2024

[RHD Genotyping Characteristics of RhD-Negative Blood Donors in Wuhu Area].

Li MN et al.

Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2024

Single-exon fetal RHD genotyping: a 31-month follow up in the obstetric population of Western Sweden.

Pardi C et al.

Blood Transfusion = Trasfusione Del Sangue, 2024

Evaluation of the LightCycler® PRO Instrument as a Platform for Rhesus D Typing.

Polin H et al.

Biomedicines, 2024

A Bioinformatically Initiated Approach to Evaluate GATA1 Regulatory Regions in Samples with Weak D, Del, or D- Phenotypes Despite Normal RHD Exons.

McGowan EC et al.

Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie, 2024

40 years of researching the Del phenotype results in a change of transfusion practice.

Flegel WA et al.

Transfusion, 2024

Identification of a novel DEL allele with c.411G>C on the RHD*01EL.01 allele background.

Shao LN et al.

Transfusion, 2024

Two Cases of Anti-D Alloimmunization in D-Negative Thai Patients as a Result of the Asian-Type DEL on Transfused Red Cells.

Suksard K et al.

Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie, 2024

Anti-D alloimmunization by Asia type DEL red blood cell units in a D-negative Thai patient.

Thongbut J et al.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis, 2023

Frequency of the 'Asia type' DEL with weak D phenotype in chinese.

Hou J et al.

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine, 2023

Noninvasive screening of fetal RHD genotype in Chinese pregnant women with serologic RhD-negative phenotype.

Duan H et al.

Transfusion, 2023

DEL variants: review of molecular mechanisms, clinical consequences and molecular testing strategy.

Yin Q

Functional & Integrative Genomics, 2023

Asian-type DEL (RHD*DEL1) with an allo-anti-D: A paradoxical observation in a healthy multiparous woman.

Ohto H et al.

Transfusion, 2023

[Molecular Mechanism of a Rhesus D Variant Individual with RHD*845A/1227A].

Xie XH et al.

Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2023

Serologically D-negative blood donors in Thailand: molecular variants and diagnostic strategy.

Nuchnoi P et al.

Blood Transfusion = Trasfusione Del Sangue, 2023

Transfusion management of Africans with RHD variants in China.

Yin Q et al.

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine, 2023

Patients with Asian-type DEL can safely be transfused with RhD-positive blood.

Ji Y et al.

Blood, 2023

RHD 1227 A and hybrid Rhesus box analysis in Thai RhD+ and RhD- blood donors: Prevalence, RHD zygosity, and molecular screening.

Simtong P et al.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis, 2022

A novel RHD allele, RHD c.56C>G (p.Thr19Arg), with Del phenotype identified in a Chinese family.

Jiang Z et al.

Transfusion, 2022

RHD alleles contributing to serologically weak D phenotypes in China: A single-centre study over 10 years.

Ye L et al.

Vox Sanguinis, 2022

A novel RHD allele, RHD*1166delA, with D-negative phenotype identified in a Chinese family.

Zhang X et al.

Transfusion, 2022

The efficacy of ethnic specific blood groups genotyping for routine donor investigation and rare donor identification in Taiwan.

Yang MH et al.

Vox Sanguinis, 2022

A practical and effective strategy in East Asia to prevent anti-D alloimmunization in patients by C/c phenotyping of serologic RhD-negative blood donors.

Ito S et al.

Ejhaem, 2021

DEL in China: the D antigen among serologic RhD-negative individuals.

Yin Q et al.

Journal of Translational Medicine, 2021

Molecular basis of serological weak D phenotypes and RhD typing discrepancies identified in the Korean population.

Chung YN et al.

Blood Transfusion = Trasfusione Del Sangue, 2021

[Molecular genetic analysis of two individuals with weak D variant of the Rh blood type].

He Y et al.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics, 2021

Nation-wide investigation of RHD variants in Thai blood donors: Impact for molecular diagnostics.

Thongbut J et al.

Transfusion, 2021

The Significance of RHD Genotyping and Characteristic Analysis in Chinese RhD Variant Individuals.

Ying Y et al.

Frontiers in Immunology, 2021

RHD Genotypes in a Chinese Cohort of Pregnant Women.

Zhang J et al.

Frontiers in Genetics, 2021

RHD genotyping is recommended for all patients with serological weak-D phenotypes in Asian populations - Cases with coexistence of weak-D and Asia type DEL alleles results in complete expression of D-antigen.

Chun S et al.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis, 2020

Comprehensive Molecular Analysis of Serologically D-Negative and Weak/Partial D Phenotype in Thai Blood Donors.

Thongbut J et al.

Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie, 2020

Molecular and computational analysis of 45 samples with a serologic weak D phenotype detected among 132,479 blood donors in northeast China.

Zhang X et al.

Journal of Translational Medicine, 2019

Characterization of RHD alleles present in serologically RHD-negative donors determined by a sensitive microplate technique.

de Paula Vendrame TA et al.

Vox Sanguinis, 2019

Amplicon Sequencing-Based Noninvasive Fetal Genotyping for RHD-Positive D Antigen-Negative Alleles.

Takahashi K et al.

Clinical Chemistry, 2019

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