Associated Papers
TNFAIP8L2 maintains hair cell function and regulates age-related hearing loss via mTORC1 signaling.
Li W et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy, 2025
IL-37d suppresses Rheb-mTORC1 axis independently of TCS2 to alleviate alcoholic liver disease.
Chen N et al.
Communications Biology, 2024
TSC-insensitive Rheb mutations induce oncogenic transformation through a combination of constitutively active mTORC1 signalling and proteome remodelling.
Xie J et al.
Cellular and Molecular Life Sciences : Cmls, 2021
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
Arhzaouy K et al.
Autophagy, 2019
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.
Walton ZE et al.
Cell, 2018
Inhibition of MAPK pathway is essential for suppressing Rheb-Y35N driven tumor growth.
Wang Y et al.
Oncogene, 2017
Recent progress in the study of the Rheb family GTPases.
Heard JJ et al.
Cellular Signalling, 2014
Rapamycin-induced autophagy aggravates pathology and weakness in a mouse model of VCP-associated myopathy.
Ching JK et al.
Autophagy, 2013
Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling.
Hanker AB et al.
Oncogene, 2010
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