Varaico: Literature-Extracted Genetic Variants

Gene:RHEB
Variant:p.R15G
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RHEB

NM_005614.4:p.R15G

Associated Papers

Development of a versatile HPLC-based method to evaluate the activation status of small GTPases.

Araki M et al.

The Journal of Biological Chemistry, 2021

TSC-insensitive Rheb mutations induce oncogenic transformation through a combination of constitutively active mTORC1 signalling and proteome remodelling.

Xie J et al.

Cellular and Molecular Life Sciences : Cmls, 2021

Structural basis for the unique biological function of small GTPase RHEB.

Yu Y et al.

The Journal of Biological Chemistry, 2005

Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells.

Im E et al.

Oncogene, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."