Associated Papers
A structurally informed human protein-protein interactome reveals proteome-wide perturbations caused by disease mutations.
Xiong D et al.
Nature Biotechnology, 2025
Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes.
Hiitola E et al.
Science Advances, 2025
Pan-cancer analyses identify oncogenic drivers, expression signatures, and therapeutic vulnerabilities in RHO GTPase pathway genes.
Fernández R et al.
Frontiers in Bioinformatics, 2025
The theory of massively repeated evolution and full identifications of cancer-driving nucleotides (CDNs).
Zhang L et al.
Elife, 2024
Oncogenic composite mutations can be predicted by co-mutations and their chromosomal location.
Küçükosmanoglu A et al.
Molecular Oncology, 2024
Pathogenic single nucleotide polymorphisms in RhoA gene: Insights into structural and functional impacts on RhoA-PLD1 interaction through molecular dynamics simulation.
Hasan M et al.
Current Research in Structural Biology, 2024
Multiancestry genomic and transcriptomic analysis of gastric cancer.
Totoki Y et al.
Nature Genetics, 2023
Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells.
Ikari N et al.
Oncology Letters, 2021
Spatially interacting phosphorylation sites and mutations in cancer.
Huang KL et al.
Nature Communications, 2021
Mutational drivers of cancer cell migration and invasion.
Novikov NM et al.
British Journal of Cancer, 2021
Somatic Evolution in Non-neoplastic IBD-Affected Colon.
Olafsson S et al.
Cell, 2020
RAS and RHO family GTPase mutations in cancer: twin sons of different mothers?
Hodge RG et al.
Critical Reviews in Biochemistry and Molecular Biology, 2020
Gene mutations distinguishing gastric from colorectal and esophageal adenocarcinomas.
Hoang T et al.
Journal of Gastrointestinal Oncology, 2020
In vivo effects of mutant RHOA on tumor formation in an orthotopic inoculation model.
Nishizawa T et al.
Oncology Reports, 2019
DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation.
Nishizawa T et al.
Oncotarget, 2018
Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.
O'Hayre M et al.
Oncogene, 2016
RHOA mutation may be associated with diffuse-type gastric cancer progression, but is it gain or loss?
Maeda M et al.
Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2016
Preferential occurrence of RHOA mutation in gastric and colorectal cancers.
Kim MS et al.
Pathology, 2015
Recurrent RHOA mutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols.
Rohde M et al.
Genes, Chromosomes & Cancer, 2014
Comprehensive molecular characterization of gastric adenocarcinoma.
Unknown Author
Nature, 2014