Associated Papers
Translating Gastric Cancer Genomics into Targeted Therapy: Mechanistic Insights from Animal Models and Patient-Derived Systems.
Shyu RY et al.
Cells, 2026
A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.
Weller C et al.
Science (new York, N.y.), 2025
Circulating Tumour DNA Is a Biomarker of Response in Angioimmunoblastic T-Cell Lymphoma.
Yannakou CK et al.
International Journal of Molecular Sciences, 2025
Reannotation of cancer mutations based on expressed RNA transcripts reveals functional non-coding mutations in melanoma.
Pepe D et al.
American Journal of Human Genetics, 2025
The role of multi-organ cancer predisposition genes in the risk of inherited and histologically diverse gastric cancer.
Guerra J et al.
Ebiomedicine, 2025
Comprehensive mapping elucidates high risk genotypes in primary metastatic breast cancer.
Berg T et al.
Neoplasia (new York, N.y.), 2025
Comprehensive immunophenotyping of gastric adenocarcinoma identifies an inflamed class of tumors amenable to immunotherapies.
Veas Rodriguez J et al.
Journal for Immunotherapy of Cancer, 2025
Identification of genomic biomarkers of disease progression and survival in primary CNS lymphoma.
Geng H et al.
Blood Advances, 2025
Refined variant calling pipeline on RNA-seq data of breast cancer cell lines without matched-normal samples.
Eberth S et al.
Bmc Research Notes, 2025
Mutations in Ras homolog family member A in patients with peripheral T-cell lymphoma and implications for personalized medicine.
Hu L et al.
Cancer Biology & Medicine, 2024
Genomic and Pathologic Profiling of Very Well-Differentiated Gastric Adenocarcinoma of Intestinal Type: A Study With Emphasis on Diffuse-Type Transformation.
Rokutan H et al.
The American Journal of Surgical Pathology, 2024
Pathogenic single nucleotide polymorphisms in RhoA gene: Insights into structural and functional impacts on RhoA-PLD1 interaction through molecular dynamics simulation.
Hasan M et al.
Current Research in Structural Biology, 2024
Angioimmunoblastic T-cell lymphoma: Novel recurrent mutations and prognostic biomarkers by cell-free DNA profiling.
Zhang C et al.
British Journal of Haematology, 2023
A Gene Panel Associated With Abemaciclib Utility in ESR1-Mutated Breast Cancer After Prior Cyclin-Dependent Kinase 4/6-Inhibitor Progression.
Brett JO et al.
Jco Precision Oncology, 2023
Unraveling the Oncogenic Potential of VAV1 in Human Cancer: Lessons from Mouse Models.
Shalom B et al.
Cells, 2023
Molecular Landscape and Association With Crohn Disease of Poorly Cohesive Carcinomas of the Nonampullary Small Bowel.
Tedaldi G et al.
American Journal of Clinical Pathology, 2023
Multiancestry genomic and transcriptomic analysis of gastric cancer.
Totoki Y et al.
Nature Genetics, 2023
Molecular characterization of adenocarcinomas arising in the urinary bladder following augmentation cystoplasty: a multi-institutional study.
Stohr BA et al.
Human Pathology, 2022
ARHGAP-RhoA signaling provokes homotypic adhesion-triggered cell death of metastasized diffuse-type gastric cancer.
Komatsu M et al.
Oncogene, 2022
Mutations Affecting Genes in the Proximal T-Cell Receptor Signaling Pathway in Peripheral T-Cell Lymphoma.
Liu X et al.
Cancers, 2022
Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.
Liu B et al.
Cancer Medicine, 2022
Early detection of T-cell lymphoma with T follicular helper phenotype by RHOA mutation analysis.
Dobson R et al.
Haematologica, 2022
Advantages and Limitations of Monitoring Circulating Tumor DNA Levels to Predict the Prognosis of Patients Diagnosed With Gastric Cancer.
He W et al.
Biomarker Insights, 2022
Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells.
Ikari N et al.
Oncology Letters, 2021
Spatially interacting phosphorylation sites and mutations in cancer.
Huang KL et al.
Nature Communications, 2021
Mutational drivers of cancer cell migration and invasion.
Novikov NM et al.
British Journal of Cancer, 2021
Characterization of the genomic landscape and actionable mutations in Chinese breast cancers by clinical sequencing.
Lang GT et al.
Nature Communications, 2020
RHOA mutation in follicular T-cell lymphoma: Clinicopathological analysis of 16 cases.
Miyoshi H et al.
Pathology International, 2020
Angioimmunoblastic T-cell lymphoma contains multiple clonal T-cell populations derived from a common TET2 mutant progenitor cell.
Yao WQ et al.
The Journal of Pathology, 2020
Gene mutations distinguishing gastric from colorectal and esophageal adenocarcinomas.
Hoang T et al.
Journal of Gastrointestinal Oncology, 2020
Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.
Yi Z et al.
Npj Breast Cancer, 2020
Analysis of error profiles in deep next-generation sequencing data.
Ma X et al.
Genome Biology, 2019
DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation.
Nishizawa T et al.
Oncotarget, 2018
Droplet digital polymerase chain reaction assay and peptide nucleic acid-locked nucleic acid clamp method for RHOA mutation detection in angioimmunoblastic T-cell lymphoma.
Tanzima Nuhat S et al.
Cancer Science, 2018
Activation of RHOA-VAV1 signaling in angioimmunoblastic T-cell lymphoma.
Fujisawa M et al.
Leukemia, 2018
Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.
Cho SY et al.
Gastroenterology, 2017
Recent Progress in the Understanding of Angioimmunoblastic T-cell Lymphoma.
Fujisawa M et al.
Journal of Clinical and Experimental Hematopathology : Jceh, 2017
Variegated RHOA mutations in human cancers.
Kataoka K et al.
Experimental Hematology, 2016
Landscape of somatic mutations in 560 breast cancer whole-genome sequences.
Nik-Zainal S et al.
Nature, 2016
RHOA mutation may be associated with diffuse-type gastric cancer progression, but is it gain or loss?
Maeda M et al.
Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2016
Variegated RHOA mutations in adult T-cell leukemia/lymphoma.
Nagata Y et al.
Blood, 2016
Clinicopathological characteristics of RHOA mutations in a Central European gastric cancer cohort.
Röcken C et al.
Journal of Clinical Pathology, 2016
Gene mutations in gastric cancer: a review of recent next-generation sequencing studies.
Lin Y et al.
Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2015
Genomic landscape and genetic heterogeneity in gastric adenocarcinoma revealed by whole-genome sequencing.
Wong SS et al.
Nature Communications, 2014