Varaico: Literature-Extracted Genetic Variants

Gene:RHOA
Variant:p.G14V
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RHOA

NM_001664.4:p.G14V

Associated Papers

Structural Dynamics of Rho GTPases.

Lin Y et al.

Journal of Molecular Biology, 2025

Function of a complex of p-Y42 RhoA GTPase and pyruvate kinase M2 in EGF signaling pathway in glioma cells.

Lee YB et al.

Journal of Neurochemistry, 2025

C1-linker region of PARG1 RhoGAP promotes the catalytic recognition fold of RhoA substrate.

Kouchi Z et al.

Plos One, 2025

Proximity-based proteomics (BioID) uncovers the Rho GTPase interactome in kidney podocytes.

Ibrahim S et al.

Frontiers in Cell and Developmental Biology, 2025

Tumor-derived RHOA mutants interact with effectors in the GDP-bound state.

Lin Y et al.

Nature Communications, 2024

39169042 (PubMed )
Supplement: 41467_2024_51445_MOESM2_ESM.pdf

Mutations in Ras homolog family member A in patients with peripheral T-cell lymphoma and implications for personalized medicine.

Hu L et al.

Cancer Biology & Medicine, 2024

RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling.

Schaefer A et al.

Science Signaling, 2023

Mutations Affecting Genes in the Proximal T-Cell Receptor Signaling Pathway in Peripheral T-Cell Lymphoma.

Liu X et al.

Cancers, 2022

Active RhoA Exerts an Inhibitory Effect on the Homeostasis and Angiogenic Capacity of Human Endothelial Cells.

Hauke M et al.

Journal of the American Heart Association, 2022

Structure of an inactive conformation of GTP-bound RhoA GTPase.

Lin Y et al.

Structure (london, England : 1993), 2021

RAS and RHO family GTPase mutations in cancer: twin sons of different mothers?

Hodge RG et al.

Critical Reviews in Biochemistry and Molecular Biology, 2020

Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer.

Zhang H et al.

Cancer Discovery, 2020

A New Rho(d) Map to Diffuse Gastric Cancer.

Benton D et al.

Cancer Discovery, 2020

Postzygotic inactivating mutations of RHOA cause a mosaic neuroectodermal syndrome.

Vabres P et al.

Nature Genetics, 2019

RHO Family GTPases in the Biology of Lymphoma.

Voena C et al.

Cells, 2019

Selection and Characterization of a Nanobody Biosensor of GTP-Bound RHO Activities.

Keller L et al.

Antibodies (basel, Switzerland), 2019

DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation.

Nishizawa T et al.

Oncotarget, 2018

RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis.

Cortes JR et al.

Cancer Cell, 2018

Recent Progress in the Understanding of Angioimmunoblastic T-cell Lymphoma.

Fujisawa M et al.

Journal of Clinical and Experimental Hematopathology : Jceh, 2017

Variegated RHOA mutations in human cancers.

Kataoka K et al.

Experimental Hematology, 2016

Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas.

Vallois D et al.

Blood, 2016

Clinicopathologic Analysis of Angioimmunoblastic T-cell Lymphoma With or Without RHOA G17V Mutation Using Formalin-fixed Paraffin-embedded Sections.

Nagao R et al.

The American Journal of Surgical Pathology, 2016

Variegated RHOA mutations in adult T-cell leukemia/lymphoma.

Nagata Y et al.

Blood, 2016

A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma.

Yoo HY et al.

Nature Genetics, 2014

Somatic RHOA mutation in angioimmunoblastic T cell lymphoma.

Sakata-Yanagimoto M et al.

Nature Genetics, 2014

Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica.

Bosch DE et al.

The Journal of Biological Chemistry, 2011

Conformations of nucleotides bound to wild type and Y78F mutant yeast guanylate kinase: proton two-dimensional transferred NOESY measurements.

Ray BD et al.

Biochemistry, 2005

16229466 (PubMed )
Supplement: bi0509088si20050720_102932.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."