Associated Papers
Ancestry-dependent patterns of somatic mosaicism and clonal hematopoiesis mutations in over 125,000 individuals reveal distinct cancer associations.
Colin-Leitzinger C et al.
Human Genomics, 2025
Insights into Nodal T-Follicular Helper Cell lymphomas and Peripheral T-Cell Lymphomas, Not Otherwise Specified, in Slovenian Patients: Mutational Landscape, Clinicopathological Characteristics, and Outcomes.
Erzar E et al.
Annals of Hematology, 2025
Clinical Validation of a Rapid Automated Lymphoma Next-Generation Sequencing Panel.
Krigstein M et al.
Annals of Laboratory Medicine, 2025
Divergent Morphologies and Common Signaling Features of Active and Inactive Oncogenic RHOA Mutants in Yeast.
Wang C et al.
Cells, 2025
Comprehensive Analysis of Human Colorectal Cancers Harboring Polymerase Epsilon Mutations.
Gibson LM et al.
International Journal of Molecular Sciences, 2025
A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.
Weller C et al.
Science (new York, N.y.), 2025
Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes.
Hiitola E et al.
Science Advances, 2025
Peripheral blood somatic mosaicism and clonal hematopoiesis across ancestry backgrounds.
Colin-Leitzinger C et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
A rare case of primary testicular follicular lymphoma in a pediatric patient.
Nguyen AJ et al.
Journal of Hematopathology, 2025
GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway.
Ikeuchi H et al.
Oncogene, 2024
Tumor-derived RHOA mutants interact with effectors in the GDP-bound state.
Lin Y et al.
Nature Communications, 2024
Mutations in Ras homolog family member A in patients with peripheral T-cell lymphoma and implications for personalized medicine.
Hu L et al.
Cancer Biology & Medicine, 2024
EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition.
Romero P et al.
Nature Communications, 2024
Characteristics and prognosis of rrDLBCL with TP53 mutations and a high-risk subgroup represented by the co-mutations of DDX3X-TP53.
Gao F et al.
Cancer Medicine, 2023
Multiancestry genomic and transcriptomic analysis of gastric cancer.
Totoki Y et al.
Nature Genetics, 2023
Diagnostic value of genetic mutation analysis and mutation profiling of cell-free DNA in intraocular fluid for vitreoretinal lymphoma.
Chen X et al.
Cancer Communications (london, England), 2022
A pilot study of the use of dynamic analysis of cell-free DNA from aqueous humor and vitreous fluid for the diagnosis and treatment monitoring of vitreoretinal lymphomas.
Wang X et al.
Haematologica, 2022
Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells.
Ikari N et al.
Oncology Letters, 2021
The Genetic Landscape of Ocular Adnexa MALT Lymphoma Reveals Frequent Aberrations in NFAT and MEF2B Signaling Pathways.
Magistri M et al.
Cancer Research Communications, 2021
Circulating Tumor DNA Analyses Predict Disease Recurrence in Non-Muscle-Invasive Bladder Cancer.
Zhang J et al.
Frontiers in Oncology, 2021
Genetic Landscape of Relapsed and Refractory Diffuse Large B-Cell Lymphoma: A Systemic Review and Association Analysis With Next-Generation Sequencing.
Gao F et al.
Frontiers in Genetics, 2021
Outcome of Targeted Therapy Recommendations for Metastatic and Recurrent Head and Neck Cancers.
Taghizadeh H et al.
Cancers, 2020
RHOA mutation in follicular T-cell lymphoma: Clinicopathological analysis of 16 cases.
Miyoshi H et al.
Pathology International, 2020
A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population.
Kang T et al.
Breast Cancer Research : Bcr, 2020
Gene mutations distinguishing gastric from colorectal and esophageal adenocarcinomas.
Hoang T et al.
Journal of Gastrointestinal Oncology, 2020
Feasibility and utility of a panel testing for 114 cancer-associated genes in a clinical setting: A hospital-based study.
Sunami K et al.
Cancer Science, 2019
Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma.
López C et al.
Nature Communications, 2019
Analysis of error profiles in deep next-generation sequencing data.
Ma X et al.
Genome Biology, 2019
A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.
Yan HHN et al.
Cell Stem Cell, 2018
DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation.
Nishizawa T et al.
Oncotarget, 2018
Activation of RHOA-VAV1 signaling in angioimmunoblastic T-cell lymphoma.
Fujisawa M et al.
Leukemia, 2018
Gastric poorly cohesive carcinoma: a correlative study of mutational signatures and prognostic significance based on histopathological subtypes.
Kwon CH et al.
Histopathology, 2018
Review of the biologic and clinical significance of genetic mutations in angioimmunoblastic T-cell lymphoma.
Fukumoto K et al.
Cancer Science, 2018
Profiling cancer-associated genetic alterations and molecular classification of cancer in Korean gastric cancer patients.
Kim Y et al.
Oncotarget, 2017
Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.
Cho SY et al.
Gastroenterology, 2017
Mutations of CREBBP and SOCS1 are independent prognostic factors in diffuse large B cell lymphoma: mutational analysis of the SAKK 38/07 prospective clinical trial cohort.
Juskevicius D et al.
Journal of Hematology & Oncology, 2017
Variegated RHOA mutations in human cancers.
Kataoka K et al.
Experimental Hematology, 2016
Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.
O'Hayre M et al.
Oncogene, 2016
RHOA mutation may be associated with diffuse-type gastric cancer progression, but is it gain or loss?
Maeda M et al.
Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2016
Clinicopathological characteristics of RHOA mutations in a Central European gastric cancer cohort.
Röcken C et al.
Journal of Clinical Pathology, 2016
Preferential occurrence of RHOA mutation in gastric and colorectal cancers.
Kim MS et al.
Pathology, 2015
Recurrent RHOA mutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols.
Rohde M et al.
Genes, Chromosomes & Cancer, 2014
RhoA mutations identified in diffuse gastric cancer.
Zhou J et al.
Cancer Cell, 2014
Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma.
Kakiuchi M et al.
Nature Genetics, 2014
A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma.
Yoo HY et al.
Nature Genetics, 2014