Associated Papers
Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.
Tiemann K et al.
Oncogene, 2019
PTEN negatively regulates mTORC2 formation and signaling in grade IV glioma via Rictor hyperphosphorylation at Thr1135 and direct the mode of action of an mTORC1/2 inhibitor.
Bhattacharya K et al.
Oncogenesis, 2016
Signaling crosstalk between the mTOR complexes.
Xie J et al.
Translation (austin, Tex.), 2014
mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
Julien LA et al.
Molecular and Cellular Biology, 2010
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