Associated Papers
ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation.
Zeng Q et al.
Elife, 2025
RNF167 mediates atypical ubiquitylation and degradation of RLRs via two distinct proteolytic pathways.
He M et al.
Nature Communications, 2025
Ectopic Expression of TRIM25 Restores RIG-I Expression and IFN Production Reduced by Multiple Enteroviruses 3Cpro.
Xiao H et al.
Virologica Sinica, 2021
USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I.
Tao X et al.
Plos Pathogens, 2020
Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor.
Zhu J et al.
Immunity, 2014
Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity.
Kuniyoshi K et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014
USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors.
Cui J et al.
Cell Research, 2014
Activation of duck RIG-I by TRIM25 is independent of anchored ubiquitin.
Miranzo-Navarro D et al.
Plos One, 2014
A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses.
Oshiumi H et al.
Plos Pathogens, 2013
Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response.
Jiang X et al.
Immunity, 2012
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity.
Zeng W et al.
Cell, 2010
Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes.
Shigemoto T et al.
The Journal of Biological Chemistry, 2009
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