Varaico: Literature-Extracted Genetic Variants

Gene:RIGI
Variant:p.K48R
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RIGI

NM_014314.4:p.K48R

Associated Papers

RNF20 dual regulation of MDA5 signaling to maintain immune homeostasis in chickens.

Wang J et al.

Journal of Virology, 2025

A tumor suppressor protein encoded by circKEAP1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity.

Zhang Y et al.

Journal of Experimental & Clinical Cancer Research : Cr, 2024

MAVS-loaded unanchored Lys63-linked polyubiquitin chains activate the RIG-I-MAVS signaling cascade.

Liu F et al.

Cellular & Molecular Immunology, 2023

Dual targeting of RIG-I and MAVS by MARCH5 mitochondria ubiquitin ligase in innate immunity.

Park YJ et al.

Cellular Signalling, 2020

E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses.

Song Y et al.

Nature Communications, 2017

TRAF5-mediated Lys-63-linked Polyubiquitination Plays an Essential Role in Positive Regulation of RORγt in Promoting IL-17A Expression.

Wang X et al.

The Journal of Biological Chemistry, 2015

Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity.

Kuniyoshi K et al.

Proceedings of the National Academy of Sciences of the United States of America, 2014

Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action.

Shi HX et al.

Plos Pathogens, 2011

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity.

Zeng W et al.

Cell, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."