Varaico: Literature-Extracted Genetic Variants

Gene:RIN3
Variant:p.W63C
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RIN3

NM_024832.5:p.W63C

Associated Papers

The Role of RIN3 Gene in Alzheimer's Disease Pathogenesis: a Comprehensive Review.

Meshref M et al.

Molecular Neurobiology, 2024

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.

Holstege H et al.

Nature Genetics, 2022

36411364 (PubMed )
Supplement: 41588_2022_1208_MOESM1_ESM.pdf

The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.

Bhattacharyya R et al.

Scientific Reports, 2022

Ras and Rab Interactor 3: From Cellular Mechanisms to Human Diseases.

Shen R et al.

Frontiers in Cell and Developmental Biology, 2022

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.

Shen R et al.

Translational Neurodegeneration, 2020

Genetic Variation in RIN3 in the Belgian Population Supports Its Involvement in the Pathogenesis of Paget's Disease of Bone and Modifies the Age of Onset.

De Ridder R et al.

Calcified Tissue International, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."