Associated Papers
Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface.
Lethier M et al.
Life Science Alliance, 2023
XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures.
Ellwanger K et al.
Life Science Alliance, 2019
The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex.
Panda S et al.
Nature Communications, 2018
ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.
Tao M et al.
Current Biology : Cb, 2009
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