Associated Papers
RIPK4-mediated MFN2 degradation drives osteogenesis through mitochondrial fragmentation and restricts myelopoiesis by blocking mitochondrial transfer.
Ding P et al.
Nature Communications, 2025
The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.
Oberbeck N et al.
Nature, 2019
Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Huang CS et al.
Structure (london, England : 1993), 2018
A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes.
De Groote P et al.
Cell Death and Differentiation, 2015
Mutations in RIPK4 cause the autosomal-recessive form of popliteal pterygium syndrome.
Kalay E et al.
American Journal of Human Genetics, 2012
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