Varaico: Literature-Extracted Genetic Variants

Gene:RIT1
Variant:p.E81Q
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RIT1

NM_006912.6:p.E81Q

Associated Papers

Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state.

Rominger MC et al.

Cell Reports, 2025

RIT1 Drives Oncogenic Transformation and Is an Actionable Target in Lung Adenocarcinoma.

Mozzarelli AM et al.

Cancer Research, 2025

Refined variant calling pipeline on RNA-seq data of breast cancer cell lines without matched-normal samples.

Eberth S et al.

Bmc Research Notes, 2025

39955561 (PubMed )
Supplement: 13104_2025_7140_MOESM3_ESM.xlsx › snv_indel_maf_less20_Project_bc

Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.

Chen S et al.

Cancer Discovery, 2022

Mutations in RIT1 cause Noonan syndrome with possible juvenile myelomonocytic leukemia but are not involved in acute lymphoblastic leukemia.

Cavé H et al.

European Journal of Human Genetics : Ejhg, 2016

Oncogenic RIT1 mutations in lung adenocarcinoma.

Berger AH et al.

Oncogene, 2014

24469055 (PubMed )
Supplement: 41388_2014_BFonc2013581_MOESM15_ESM.pdf

Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies.

Gómez-Seguí I et al.

Leukemia, 2013

[Mutation and amplification of RIT1 gene in hepatocellular carcinoma].

Li JT et al.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."