Varaico: Literature-Extracted Genetic Variants

Gene:RNASEH2A
Variant:p.D34A
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RNASEH2A

NM_006397.3:p.D34A

Associated Papers

RTF2 controls replication repriming and ribonucleotide excision at the replisome.

Conti BA et al.

Nature Communications, 2024

RTF2 controls replication repriming and ribonucleotide excision at the replisome.

Conti BA et al.

Biorxiv : the Preprint Server for Biology, 2023

RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition.

Benitez-Guijarro M et al.

The Embo Journal, 2018

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions.

Zimmermann M et al.

Nature, 2018

Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair.

Ghodgaonkar MM et al.

Molecular Cell, 2013

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

Reijns MA et al.

Cell, 2012

The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease.

Reijns MA et al.

The Journal of Biological Chemistry, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."