Varaico: Literature-Extracted Genetic Variants

Gene:RNASEL
Variant:p.I97L
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RNASEL

NM_021133.4:p.I97L

Associated Papers

ATR&RNASEL germline variants: novel findings in a case of familial cancer.

Biswas S et al.

Molecular Genetics and Genomics : Mgg, 2025

Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.

Lee D et al.

Science (new York, N.y.), 2023

36538032 (PubMed )
Supplement: science.abo3627_sm.pdf

Activated leukocyte cell adhesion molecule/cluster of differentiation 166 rs10933819 (G>A) variant is associated with familial intracranial aneurysms.

Aitkulova A et al.

Biomedical Reports, 2022

35815187 (PubMed )
Supplement: Supplementary_Data.xlsx › 713_shortlisted_variants

Sequence and Structure-Based Analyses of Human Ankyrin Repeats.

Chakrabarty B et al.

Molecules (basel, Switzerland), 2022

35056738 (PubMed )
Supplement: molecules-27-00423-s001.zip › SupplementaryFileS4.xlsx › Sheet1

Limited Practical Utility of Liquid Biopsy in the Treated Patients with Advanced Breast Cancer.

Niwinska A et al.

Diagnostics (basel, Switzerland), 2020

32731384 (PubMed )
Supplement: diagnostics-10-00523-s001.zip › diagnostics-851816-supplementary.xlsx › Supplementary_Table_S2

Precision Health Resource of Control iPSC Lines for Versatile Multilineage Differentiation.

Hildebrandt MR et al.

Stem Cell Reports, 2019

31813827 (PubMed )
Supplement: mmc2.xlsx › SNVs

Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes.

Karyadi DM et al.

Oncotarget, 2017

27902461 (PubMed )
Supplement: oncotarget-08-1495-s003.xlsx › Sheet1

Prognostic role of genetic biomarkers in clinical progression of prostate cancer.

Alvarez-Cubero MJ et al.

Experimental & Molecular Medicine, 2015

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.

Karageorgos I et al.

Human Genomics, 2015

26092435 (PubMed )
Supplement: 40246_2015_34_MOESM1_ESM.xlsx › FamilyA

Prostate Cancer Genetics: A Review.

Wallis CJ et al.

Ejifcc, 2015

Functional and Structural Consequences of Damaging Single Nucleotide Polymorphisms in Human Prostate Cancer Predisposition Gene RNASEL.

Datta A et al.

Biomed Research International, 2015

[Hereditary prostate cancer].

Heise M et al.

Postepy Higieny I Medycyny Doswiadczalnej (online), 2014

Association of RNASEL and 8q24 variants with the presence and aggressiveness of hereditary and sporadic prostate cancer in a Hispanic population.

San Francisco IF et al.

Journal of Cellular and Molecular Medicine, 2014

Genetic analysis of the principal genes related to prostate cancer: a review.

Alvarez-Cubero MJ et al.

Urologic Oncology, 2013

The potential impact of adding genetic markers to clinical parameters in managing high-risk prostate cancer patients.

Alvarez-Cubero MJ et al.

Springerplus, 2013

Predictive value in the analysis of RNASEL genotypes in relation to prostate cancer.

Alvarez-Cubero MJ et al.

Prostate Cancer and Prostatic Diseases, 2012

Genetic variation in RNASEL and risk for prostate cancer in a population-based case-control study.

Fesinmeyer MD et al.

The Prostate, 2011

[RNase L, a crucial mediator of innate immunity and other cell functions].

Bisbal C et al.

Medecine Sciences : M/s, 2008

SNPs associated with prostate cancer risk and prognosis.

Naylor SL

Frontiers in Bioscience : a Journal and Virtual Library, 2007

[Molecular basis of hereditary hemochromatosis].

Romanowski T et al.

Postepy Higieny I Medycyny Doswiadczalnej (online), 2006

RNASEL germline variants are associated with pancreatic cancer.

Bartsch DK et al.

International Journal of Cancer, 2005

Mutation screening and association study of RNASEL as a prostate cancer susceptibility gene.

Maier C et al.

British Journal of Cancer, 2005

Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates.

Xiang Y et al.

Cancer Research, 2003

RNASEL mutations in hereditary prostate cancer.

Chen H et al.

Journal of Medical Genetics, 2003

Implications for RNase L in prostate cancer biology.

Silverman RH

Biochemistry, 2003

Analysis of the RNASEL gene in familial and sporadic prostate cancer.

Wang L et al.

American Journal of Human Genetics, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."