Varaico: Literature-Extracted Genetic Variants

Gene:RNF126
Variant:p.Q77K
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RNF126

NM_194460.3:p.Q77K

Associated Papers

An essential role of the E3 ubiquitin ligase RNF126 in ensuring meiosis I completion during spermatogenesis.

Liu W et al.

Journal of Advanced Research, 2025

RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy.

Liu W et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2023

A Novel Role for RNF126 in the Promotion of G2 Arrest via Interaction With 14-3-3σ.

Fa P et al.

International Journal of Radiation Oncology, Biology, Physics, 2022

RNF126 promotes homologous recombination via regulation of E2F1-mediated BRCA1 expression.

Wang Y et al.

Oncogene, 2016

The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor.

Smith CJ et al.

Journal of Cell Science, 2013

E3 ubiquitin ligase RNF126 promotes cancer cell proliferation by targeting the tumor suppressor p21 for ubiquitin-mediated degradation.

Zhi X et al.

Cancer Research, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."