Varaico: Literature-Extracted Genetic Variants

Gene:RNF168
Variant:p.C19S
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RNF168

NM_152617.4:p.C19S

Associated Papers

The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.

Xie X et al.

Nature Cell Biology, 2018

RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1.

Muñoz MC et al.

The Journal of Biological Chemistry, 2012

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.

Stewart GS et al.

Cell, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."