Varaico: Literature-Extracted Genetic Variants

Gene:RNF31
Variant:p.L154M
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RNF31

NM_017999.5:p.L154M

Associated Papers

STK4 inhibits the E3 activity of HOIP by phosphorylating its allosteric ubiquitin-binding site.

Wang Y et al.

Cell Discovery, 2025

40957900 (PubMed )
Supplement: 41421_2025_824_MOESM2_ESM.pdf

The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains.

Rodriguez Carvajal A et al.

Elife, 2021

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate.

Stieglitz B et al.

Embo Reports, 2012

22791023 (PubMed )
Supplement: embor2012105s1.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."