Varaico: Literature-Extracted Genetic Variants

Gene:RNF43
Variant:p.G447E
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RNF43

NM_017763.6:p.G447E

Associated Papers

A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.

Tsukiyama T et al.

Nature Communications, 2020

Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.

Li S et al.

Oncogene, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."